[PDF][PDF] Potential targets for prevention of colorectal cancer: a focus on PI3K/Akt/mTOR and Wnt pathways

AK Pandurangan - Asian Pacific journal of cancer …, 2013 - pdfs.semanticscholar.org
Colorectal cancer (CRC) is one of the most common cancers in many parts of the world. Its
development is a multi-step process involving three distinct stages, initiation that alters the …

Luteolin, a bioflavonoid inhibits colorectal cancer through modulation of multiple signaling pathways: a review

AK Pandurangan, NM Esa - Asian Pacific Journal of Cancer …, 2014 - koreascience.kr
Abstract Luteolin, 3', 4', 5, 7-tetrahydroxyflavone, belongs to a group of naturally occurring
compounds called flavonoids that are found widely in the plant kingdom. It possesses many …

Deciphering the Potential Neuroprotective Effects of Luteolin against Aβ142-Induced Alzheimer's Disease

S Ahmad, MH Jo, M Ikram, A Khan, MO Kim - International Journal of …, 2021 - mdpi.com
The current study was undertaken to unveil the protective effects of Luteolin, a natural
flavonoid, against amyloid-beta (Aβ1–42)-induced neuroinflammation, amyloidogenesis …

Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2) …

YS Chiou, ML Tsai, K Nagabhushanam… - Journal of agricultural …, 2011 - ACS Publications
Inflammatory bowel diseases have been a risk factor of colorectal cancer (CRC). The
reactive oxygen species (ROS) generated by inflammatory cells create oxidative stress and …

Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR‑384/pleiotrophin axis

Y Yao, C Rao, G Zheng, S Wang - Oncology reports, 2019 - spandidos-publications.com
Abstract Luteolin (3, 4, 5, 7‑tetrahydroxyflavone) is a natural flavonoid that has been found to
exhibit anticancer properties in certain types of cancers. In the present study, the role of …

Flavonoids nanostructures promising therapeutic efficiencies in colorectal cancer

S Hassani, H Maghsoudi, F Fattahi… - International Journal of …, 2023 - Elsevier
Colorectal cancer is among the frequently diagnosed cancers with high mortality rates
around the world. Polyphenolic compounds such as flavonoids are secondary plant …

Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice

AK Pandurangan, N Mohebali… - Drug design …, 2015 - Taylor & Francis
Gallic acid (GA) is a polyhydroxy phenolic compound that has been detected in various
natural products, such as green tea, strawberries, grapes, bananas, and many other fruits. In …

Cannabinoids, endocannabinoids, and related analogs in inflammation

SH Burstein, RB Zurier - The AAPS journal, 2009 - Springer
This review covers reports published in the last 5 years on the anti-inflammatory activities of
all classes of cannabinoids, including phytocannabinoids such as tetrahydrocannabinol and …

Luteolin induced G2 phase cell cycle arrest and apoptosis on non-small cell lung cancer cells

X Cai, T Ye, C Liu, W Lu, M Lu, J Zhang, M Wang… - Toxicology in vitro, 2011 - Elsevier
In this study, we investigated the underlying molecular mechanism for the potent cell cycle
inhibition and pro-apoptotic effect of luteolin (2-(3, 4-dihydroxyphenyl)-5, 7-dihydroxy-4 …

Natural flavonoids for the prevention of colon cancer: A comprehensive review of preclinical and clinical studies

K Afshari, NS Haddadi, A Haj‐Mirzaian… - Journal of cellular …, 2019 - Wiley Online Library
Flavonoids comprise a group of natural polyphenols consisting of more than 5,000 subtypes
mostly existing in fruits and vegetables. Flavonoids consumption could potentially attenuate …