Hypothyroidism following radiotherapy for head and neck cancer: a systematic review of the literature and opportunities to improve the therapeutic ratio

MK Rooney, LM Andring, KL Corrigan, V Bernard… - Cancers, 2023 - mdpi.com
Simple Summary Hypothyroidism is a common toxicity experienced after radiotherapy for
head and neck malignancies. In this systemic review of the literature, we consolidated the …

[HTML][HTML] Dose-volume predictors of post-radiation primary hypothyroidism in head and neck cancer: A systematic review

JCH Chow, KM Cheung, GTC Cheung… - Clinical and translational …, 2022 - Elsevier
Abstract Background and Purpose This systematic review aims to identify radiation dose-
volume predictors of primary hypothyroidism after radiotherapy in patients with head and …

[HTML][HTML] Thyroid volume changes following adjuvant radiation therapy for breast cancer

J Roberson, H Huang, C Noldner, W Hou… - Clinical and …, 2023 - Elsevier
Background and purpose Incidental thyroid gland irradiation frequently occurs in breast
cancer patients who receive regional nodal irradiation (RNI) to the supraclavicular (SCV) …

Prediction of radiation-induced hypothyroidism using radiomic data analysis does not show superiority over standard normal tissue complication models

U Smyczynska, S Grabia, Z Nowicka, A Papis-Ubych… - Cancers, 2021 - mdpi.com
Simple Summary Radiation-induced hypothyroidism (RIHT) commonly develops in cancer
survivors that receive radiation therapy for cancers in the head and neck region. The state-of …

Risk factors of early thyroid dysfunction after definitive radiotherapy in nasopharyngeal carcinoma patients

CL Lian, RG Zhuo, R Zhou, YF Yu, P Zhou, Q Lin… - Head & …, 2023 - Wiley Online Library
Background To explore the patterns and risk factors of early thyroid dysfunction in
nasopharyngeal carcinoma (NPC) patients within 1 year after intensity‐modulated radiation …

Radiation Therapy for HPV-Positive Oropharyngeal Squamous Cell Carcinoma: An ASTRO Clinical Practice Guideline

DN Margalit, CJ Anker, M Aristophanous… - Practical Radiation …, 2024 - Elsevier
Purpose HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) is a distinct
disease from other head and neck tumors. This guideline provides evidence-based …

Radiation-induced hypothyroidism in patients with oropharyngeal cancer treated with imrt: Independent and external validation of five normal tissue complication …

Z Nowicka, B Tomasik, A Papis-Ubych, R Bibik… - Cancers, 2020 - mdpi.com
Simple Summary Hypothyroidism is a common complication of therapeutic irradiation in the
neck area. Several dose-response models have been proposed to predict its' occurrence …

Development and validation of a machine learning model of radiation-induced hypothyroidism with clinical and dose–volume features

MH Tsai, JTC Chang, HH Lu, YH Wu, TH Pao… - Radiotherapy and …, 2023 - Elsevier
Background and purpose Radiation-induced hypothyroidism (RIHT) is a common but
underestimated late effect in head and neck cancers. However, no consensus exists …

[HTML][HTML] An Analytical Study to Determine Dose-Volume Threshold for Radiation Induced Hypothyroidism

K Pravesh, P Sethi, SK Kamalanathan… - Asian Pacific Journal …, 2023 - ncbi.nlm.nih.gov
Objective: To determine radiation dose volume threshold in predicting the development of
hypothyroidism in cancer patients following neck irradiation. Methods: This is a cross …

[HTML][HTML] Dosimetric and radiobiological analyses of a de-escalation strategy for elective nodal regions in human papillomavirus-associated oropharyngeal cancer

N Tomita, N Hayashi, T Mizuno, Y Kitagawa… - Technical Innovations & …, 2023 - Elsevier
Introduction In this simulation study, we examined the effects of a de-escalation strategy with
a reduced dose to subclinical nodal regions in patients with human papillomavirus (HPV) …