The sympathetic nervous system maintains metabolic homeostasis by orchestrating the
activity of organs such as the pancreas, liver, and white and brown adipose tissues. From …

Protein phosphorylation is an important post‐transcriptional modification involving an
extremely wide range of intracellular signaling transduction pathways, making it an …

Brown adipose tissue (BAT)-mediated thermogenesis declines with age. However, the
underlying mechanism remains unclear. Here we reveal that bone marrow-derived pro …

Sympathetic innervation is essential for the development of functional beige fat that
maintains body temperature and metabolic homeostasis, yet the molecular mechanisms …

Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …

The incidence of metabolism-related diseases like obesity and type 2 diabetes mellitus has
reached pandemic levels worldwide and increased gradually. Most of them are listed on the …

The stellate ganglia play an important role in cardiac remodeling after myocardial infarction
(MI). This study aimed to investigate whether adiponectin (APN), an adipokine mainly …

Background Cancer-associated cachexia is a multi-organ disorder associated with
progressive weight loss due to a variable combination of anorexia, systemic inflammation …

Bioactive macromolecular drugs known as Growth Factors (GFs), approved by the Food and
Drug Administration (FDA), have found successful application in clinical practice. They hold …

Obesity is a complex, multifactorial, and relapsing disease whose prevalence has tripled
during the last decades and whose incidence is expected to further increase. For these …