Resolving the prefrontal mechanisms of adaptive cognitive behaviors: A cross-species perspective

IL Hanganu-Opatz, T Klausberger, T Sigurdsson… - Neuron, 2023 - cell.com
The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

Prefrontal circuits encode both general danger and specific threat representations

M Martin-Fernandez, AP Menegolla… - Nature …, 2023 - nature.com
Behavioral adaptation to potential threats requires both a global representation of danger to
prepare the organism to react in a timely manner but also the identification of specific …

[HTML][HTML] Neural oscillations in aversively motivated behavior

MS Totty, S Maren - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Fear and anxiety-based disorders are highly debilitating and among the most prevalent
psychiatric disorders. These disorders are associated with abnormal network oscillations in …

[HTML][HTML] The dynamic state of a prefrontal–hypothalamic–midbrain circuit commands behavioral transitions

C Chen, M Altafi, MA Corbu, A Trenk… - Nature …, 2024 - nature.com
Innate behaviors meet multiple needs adaptively and in a serial order, suggesting the
existence of a hitherto elusive brain dynamics that brings together representations of …

[HTML][HTML] Ventromedial prefrontal neurons represent self-states shaped by vicarious fear in male mice

Z Huang, M Chung, K Tao, A Watarai, MY Wang… - Nature …, 2023 - nature.com
Perception of fear induced by others in danger elicits complex vicarious fear responses and
behavioral outputs. In rodents, observing a conspecific receive aversive stimuli leads to …

[HTML][HTML] Early selection of task-relevant features through population gating

J Barbosa, R Proville, CC Rodgers… - Nature …, 2023 - nature.com
Brains can gracefully weed out irrelevant stimuli to guide behavior. This feat is believed to
rely on a progressive selection of task-relevant stimuli across the cortical hierarchy, but the …

BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking

CJ Gabriel, Z Zeidler, B Jin, C Guo, CM Goodpaster… - Elife, 2022 - elifesciences.org
Quantitative descriptions of animal behavior are essential to study the neural substrates of
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …

[HTML][HTML] Population-level coding of avoidance learning in medial prefrontal cortex

B Ehret, R Boehringer, EA Amadei, MR Cervera… - Nature …, 2024 - nature.com
The medial prefrontal cortex (mPFC) has been proposed to link sensory inputs and
behavioral outputs to mediate the execution of learned behaviors. However, how such a link …

A distinct cortical code for socially learned threat

SE Silverstein, R O'Sullivan, O Bukalo, D Pati… - Nature, 2024 - nature.com
Animals can learn about sources of danger while minimizing their own risk by observing
how others respond to threats. However, the distinct neural mechanisms by which threats …

The medial prefrontal regulation of maternal behavior across postpartum: A triadic model.

M Li - Psychological review, 2023 - psycnet.apa.org
Maternal behavior is a highly motivated and adaptive social behavior. Its frequency and
pattern change across the postpartum period in response to the changing characteristics of …