1, 3, 4-Thiadiazole: synthesis, reactions, and applications in medicinal, agricultural, and materials chemistry

Y Hu, CY Li, XM Wang, YH Yang, HL Zhu - Chemical reviews, 2014 - ACS Publications
Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …

1, 3, 4‐Thiadiazole and its derivatives: A review on recent progress in biological activities

AK Jain, S Sharma, A Vaidya… - Chemical biology & …, 2013 - Wiley Online Library
The 1, 3, 4‐thiadiazole nucleus is one of the most important and well‐known heterocyclic
nuclei, which is a common and integral feature of a variety of natural products and medicinal …

Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings

P Majumdar, A Pati, M Patra, RK Behera… - Chemical …, 2014 - ACS Publications
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …

2-Amino-1, 3, 4-thiadiazole as a potential scaffold for promising antimicrobial agents

G Serban, O Stanasel, E Serban… - Drug design, development …, 2018 - Taylor & Francis
Pathogenic microorganisms are causative agents for different types of serious and even
lethal infectious diseases. Despite advancements in medication, bacterial and fungal …

Thiadiazole—A promising structure in medicinal chemistry

Y Li, J Geng, Y Liu, S Yu, G Zhao - ChemMedChem, 2013 - Wiley Online Library
Many compounds containing a five‐membered heterocyclic ring display exceptional
chemical properties and versatile biological activities. In this Minireview, thiadiazoles are …

Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1, 3, 4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1, 3, 4 …

AA Kadi, NR El-Brollosy, OA Al-Deeb, EE Habib… - European journal of …, 2007 - Elsevier
Reaction of 1-adamantanecarbonyl chloride with certain carboxylic acid hydrazides in
pyridine yielded the corresponding N-acyl adamantane-1-carbohydrazide derivatives 3a–j …

1, 3, 4-Thiadiazoles: A potent multi targeted pharmacological scaffold

S Haider, MS Alam, H Hamid - European journal of medicinal chemistry, 2015 - Elsevier
Despite a significant work on thiadiazoles, continuous efforts are still being made to identify
novel heterocyclic compounds with potent biological activities. This review may help the …

Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents

AA Bekhit, HMA Ashour, YSA Ghany… - European journal of …, 2008 - Elsevier
Four series of pyrazolyl benzenesulfonamide derivatives have been synthesized. The first
series was prepared by cyclization of the intermediate N, N-dimethylaminomethylene-4 [3 …

Synthesis and anticancer activity of 5-(3-indolyl)-1, 3, 4-thiadiazoles

D Kumar, NM Kumar, KH Chang, K Shah - European journal of medicinal …, 2010 - Elsevier
A series of 5-(3-indolyl)-2-substituted-1, 3, 4-thiadiazoles 5a–m were synthesized and their
cytotoxicity analyzed against six human cancer cell lines. The reaction of indole-3-carboxylic …

Synthesis and antimicrobial activity evaluation of new 1, 2, 4-triazoles and 1, 3, 4-thiadiazoles bearing imidazo [2, 1-b] thiazole moiety

NU Güzeldemirci, Ö Küçükbasmacı - European journal of medicinal …, 2010 - Elsevier
A series of 4-alkyl/aryl-2, 4-dihydro-5-((6-(4-bromophenyl) imidazo [2, 1-b] thiazol-3-yl)
methyl)-3H-1, 2, 4-triazole-3-thiones (3a–i) and 2-alkyl/arylamino-5-((6-(4-bromophenyl) …