Mitochondrial DNA copy number and risk of diabetes mellitus and metabolic syndrome
C Huang, L Chen, J Li, J Ma, J Luo, Q Lv… - The Journal of …, 2024 - academic.oup.com
Abstract Context Mitochondrial DNA (mtDNA) plays a key role in diabetes mellitus and
metabolic syndrome (MetS). An increasing number of studies have reported the association …
metabolic syndrome (MetS). An increasing number of studies have reported the association …
The role of mitochondrial DNA copy number in cardiometabolic disease: a bidirectional two-sample mendelian randomization study
P Qin, T Qin, L Liang, X Li, B Jiang, X Wang… - Cardiovascular …, 2024 - Springer
Background This study used a bidirectional 2-sample Mendelian randomization study to
investigate the potential causal links between mtDNA copy number and cardiometabolic …
investigate the potential causal links between mtDNA copy number and cardiometabolic …
Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation
Mitochondrial DNA copy number (mtDNA-CN) measured from blood specimens is a
minimally invasive marker of mitochondrial function that exhibits both inter-individual and …
minimally invasive marker of mitochondrial function that exhibits both inter-individual and …
Association of mitochondrial DNA copy number with cardiometabolic diseases
Mitochondrial DNA (mtDNA) is present in multiple copies in human cells. We evaluated
cross-sectional associations of whole-blood mtDNA copy number (CN) with several …
cross-sectional associations of whole-blood mtDNA copy number (CN) with several …
Mitochondrial DNA copy number: linking diabetes and cancer
AA Memon, S Vats, J Sundquist, Y Li… - Antioxidants & Redox …, 2022 - liebertpub.com
Recent Advances: Various studies have suggested that mitochondrial DNA copy number
(mtDNA-CN), a surrogate biomarker of mitochondrial dysfunction, is an easily quantifiable …
(mtDNA-CN), a surrogate biomarker of mitochondrial dysfunction, is an easily quantifiable …
[HTML][HTML] Sodium-glucose cotransporter 2 inhibitors and mitochondrial functions: state of the art
Sodium-glucose cotransporter 2 inhibitors (SGLT2is) are a class of newly introduced
antidiabetic drugs with potent hypoglycemic effects. Recent evidence suggests that these …
antidiabetic drugs with potent hypoglycemic effects. Recent evidence suggests that these …
The anti-obesity potential of superparamagnetic iron oxide nanoparticles against high-fat diet-induced obesity in rats: Possible involvement of mitochondrial …
Background: Obesity is a pandemic disease that is rapidly growing into a serious health
problem and has economic impact on healthcare systems. This bleak image has elicited …
problem and has economic impact on healthcare systems. This bleak image has elicited …
Mitochondrial DNA copy number, metabolic syndrome, and insulin sensitivity: Insights from the Sugar, Hypertension, and Physical Exercise studies
SY Yang, CS Mirabal, CE Newcomb, KJ Stewart… - PloS one, 2022 - journals.plos.org
Mitochondrial DNA copy number (mtDNA-CN) measured in blood has been associated with
many aging-related diseases, with higher mtDNA-CN typically associated with lower …
many aging-related diseases, with higher mtDNA-CN typically associated with lower …
Mitochondrial DNA copy number is associated with incident chronic kidney disease and proteinuria in the AIDS linked to the intravenous experience cohort
We evaluated the prospective association of mitochondrial DNA copy number (mtDNA CN)
with markers of kidney function among a cohort of persons who inject drugs (PWID). This is a …
with markers of kidney function among a cohort of persons who inject drugs (PWID). This is a …
Assessment of the bi-directional relationship between blood mitochondrial DNA copy number and type 2 diabetes mellitus: a multivariable-adjusted regression and …
Aims/hypothesis Mitochondrial dysfunction, which can be approximated by blood
mitochondrial DNA copy number (mtDNA-CN), has been implicated in the pathogenesis of …
mitochondrial DNA copy number (mtDNA-CN), has been implicated in the pathogenesis of …