Acinetobacter baumannii biofilms: effects of physicochemical factors, virulence, antibiotic resistance determinants, gene regulation, and future antimicrobial treatments

EC Eze, HY Chenia, ME El Zowalaty - Infection and drug …, 2018 - Taylor & Francis
Acinetobacter baumannii is a leading cause of nosocomial infections due to its increased
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …

The FUR (ferric uptake regulator) superfamily: diversity and versatility of key transcriptional regulators

MF Fillat - Archives of biochemistry and biophysics, 2014 - Elsevier
Control of metal homeostasis is essential for life in all kingdoms. In most prokaryotic
organisms the FUR (ferric uptake regulator) family of transcriptional regulators is involved in …

Metal limitation and toxicity at the interface between host and pathogen

KW Becker, EP Skaar - FEMS microbiology reviews, 2014 - academic.oup.com
Metals are required cofactors for numerous fundamental processes that are essential to both
pathogen and host. They are coordinated in enzymes responsible for DNA replication and …

[HTML][HTML] Factors mediating Acinetobacter baumannii biofilm formation: Opportunities for developing therapeutics

K Upmanyu, QMR Haq, R Singh - Current Research in Microbial Sciences, 2022 - Elsevier
Acinetobacter baumannii has notably become a superbug due to its mounting risk of
infection and escalating rates of antimicrobial resistance, including colistin, the last-resort …

Interplay between iron homeostasis and virulence: Fur and RyhB as major regulators of bacterial pathogenicity

G Porcheron, CM Dozois - Veterinary microbiology, 2015 - Elsevier
In bacteria–host interactions, competition for iron is critical for the outcome of the infection.
As a result of its redox properties, this metal is essential for the growth and proliferation of …

Vibrio iron transport: evolutionary adaptation to life in multiple environments

SM Payne, AR Mey, EE Wyckoff - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Iron is an essential element for Vibrio spp., but the acquisition of iron is complicated by its
tendency to form insoluble ferric complexes in nature and its association with high-affinity …

Modulation of quorum sensing and biofilms in less investigated gram-negative ESKAPE pathogens

V Lazar, AM Holban, C Curutiu… - Frontiers in Microbiology, 2021 - frontiersin.org
Pathogenic bacteria have the ability to sense their versatile environment and adapt by
behavioral changes both to the external reservoirs and the infected host, which, in response …

Phylogeny and life cycle of the zoonotic pathogen Vibrio vulnificus

C Hernández‐Cabanyero… - Environmental …, 2020 - Wiley Online Library
Vibrio vulnificus is a zoonotic pathogen able to cause diseases in humans and fish that
occasionally result in sepsis and death. Most reviews about this pathogen (including those …

Iron is a signal for Stenotrophomonas maltophilia biofilm formation, oxidative stress response, OMPs expression, and virulence

CA Garcia, ES Alcaraz, MA Franco… - Frontiers in …, 2015 - frontiersin.org
Stenotrophomonas maltophilia is an emerging nosocomial pathogen. In many bacteria iron
availability regulates, through the Fur system, not only iron homeostasis but also virulence …

The role of Vibrio vulnificus virulence factors and regulators in its infection-induced sepsis

G Li, MY Wang - Folia microbiologica, 2020 - Springer
Due to the development of Marine aquaculture, infections caused by Vibrio vulnificus are
common all over the world. Symptoms of V. vulnificus infection vary from gastrointestinal …