Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Surface topography impacts on cell growth and differentiation, but it is not trivial to generate
defined surface structures and to assess the relevance of specific topographic parameters …

Topography, among other physical factors such as substrate stiffness and extracellular
forces, is known to have a great influence on cell behaviours. Optimization of topographical …

Nanocomposites have emerged in the last two decades as an efficient strategy to upgrade
the structural and functional properties of synthetic polymers. Aliphatic polyesters as …

Cells within tissues are continuously exposed to physical forces including hydrostatic
pressure, shear stress, and compression and tension forces. Cells dynamically adapt to …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

During the last few years, research on toxicologically relevant properties of engineered
nanoparticles has increased tremendously. A number of international research projects and …

The nanoscale surface topography of artificial materials is known to play a significant role in
interactions with biological systems such as proteins and cells. A detailed understanding …

In the process of bone regeneration, new bone formation is largely affected by physico-
chemical cues in the surrounding microenvironment. Tissue cells reside in a complex …