In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

All organisms growing beyond the oxygen diffusion limit critically depend on a functional
vasculature for survival. Yet blood vessels are far more than passive, uniform conduits for …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

The vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor
(VEGFR) axis is indispensable in the process of angiogenesis and has been implicated as a …

The vast blood-vessel network of the circulatory system is crucial for maintaining bodily
homeostasis, delivering essential molecules and blood cells, and removing waste products …

Blood vessels form extensive networks that nurture all tissues in the body. Abnormal vessel
growth and function are hallmarks of cancer and ischemic and inflammatory diseases, and …

The vertebrate vasculature forms an extensive branched network of blood vessels that
supplies tissues with nutrients and oxygen. During vascular development, coordinated …

Aerobic exercise in young adults can induce vascular plasticity in the hippocampus, a critical
region for recall and recognition memory. In a mechanistic proof-of-concept intervention over …

The endothelium is the cell monolayer that lines the interior of the blood vessels separating
the vessel lumen where blood circulates, from the surrounding tissues. During embryonic …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …