Complications and challenges associated with polycystic ovary syndrome: current perspectives

S Palomba, S Santagni, A Falbo… - International journal of …, 2015 - Taylor & Francis
Polycystic ovary syndrome (PCOS) represents the most common endocrine dysfunction in
fertile women and it is considered a heterogeneous and multifaceted disorder, with multiple …

Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review

S Palomba, A Falbo, F Zullo, F Orio Jr - Endocrine reviews, 2009 - academic.oup.com
Metformin is an insulin sensitizer widely used for the treatment of patients affected by type 2
diabetes mellitus. Because many women with polycystic ovary syndrome (PCOS) are insulin …

Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome

E Diamanti-Kandarakis, CD Christakou… - European journal of …, 2010 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized to be the most common
endocrinopathy in women of reproductive age with a prevalence of 6.6–6.8%. PCOS, a …

Role of metformin in the management of polycystic ovary syndrome

H Lashen - Therapeutic advances in endocrinology and …, 2010 - journals.sagepub.com
Polycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of
women and also the most controversial. Metformin was logically introduced to establish the …

High and low BMI increase the risk of miscarriage after IVF/ICSI and FET

Z Veleva, A Tiitinen, S Vilska… - Human …, 2008 - academic.oup.com
BACKGROUND The extremes of BMI are associated with an increased risk of miscarriage
both in spontaneously conceived pregnancies and after fertility treatment. The aim of the …

Recurrent miscarriage: pathophysiology and outcome

B Carrington, G Sacks, L Regan - Current Opinion in Obstetrics …, 2005 - journals.lww.com
With the exception of aspirin and heparin for the prevention of recurrent miscarriage in
women with the antiphospholipid syndrome, no other suggested therapies for this …

Emerging role for dysregulated decidualization in the genesis of preeclampsia

KP Conrad, MB Rabaglino, EDP Uiterweer - Placenta, 2017 - Elsevier
In normal human placentation, uterine invasion by trophoblast cells and subsequent spiral
artery remodeling depend on cooperation among fetal trophoblasts and maternal decidual …

The role of obesity in the development of polycystic ovary syndrome

A Beatriz Motta - Current pharmaceutical design, 2012 - ingentaconnect.com
Polycystic Ovary Syndrome (PCOS) is one of the common endocrine diseases that affects
women in their reproductive age. PCOS has diverse clinical implications that include …

[HTML][HTML] Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

S Palomba, A Falbo, F Orio Jr, F Zullo - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To evaluate the effect of pregestational metformin administration on abortion
risk in polycystic ovary syndrome (PCOS) patients. DESIGN: Systematic review and meta …

High fasting insulin levels and insulin resistance may be linked to idiopathic recurrent pregnancy loss: a case‐control study

CA Ispasoiu, R Chicea, FV Stamatian… - International Journal of …, 2013 - Wiley Online Library
Objective. Patients with more than two spontaneous pregnancy losses are diagnosed with
recurrent pregnancy loss. The aim of this study was to evaluate the IR (insulin resistance) in …