Several studies have indicated an overlap between gastroesophageal reflux disease
(GERD) and various functional gastrointestinal disorders (FGIDs). The overlapping …

Nonerosive reflux disease (NERD) represents the more common phenotypic presentation of
GERD and comprises patients who have typical symptoms without any mucosal breaks at …

Functional esophageal disorders consist of a disease category that presents with
esophageal symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by …

Background Recently, it has been suggested that low esophageal basal impedance may
reflect impaired mucosal integrity and increased acid sensitivity. We aimed to compare …

Background A short‐course of proton pump inhibitors (PPI s) is often used to confirm
gastroesophageal reflux disease (GERD). However, some patients with PPI responsive …

Heartburn is a common symptom in clinical practice, but as many as 70% of patients have
normal findings from upper endoscopy. Most of these patients have nonerosive reflux …

This is easily the most focused and comprehensive book available dedicated to the
esophagus and its conditions, fully exploring anatomy, physiology, pathology, diagnosis …

Methods Patients with heartburn from the Beijing Anzhen Hospital, who underwent upper
gastrointestinal endoscopy and 24-hour MII/pH, were enrolled in this study. Results In all, 24 …

The definition of functional heartburn has been refined over the years. It is currently
described, based upon Rome IV criteria, as typical heartburn symptoms in the presence of …

Heartburn is among the most common gastrointestinal symptoms presenting to both
generalist physicians and gastroenterologists. Heartburn that does not respond to traditional …