Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Cell membranes are the initial site of stimulus perception from environment and
phospholipids are the basic and important components of cell membranes. Phospholipases …

The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Abstract Phospholipases D (PLD) and C (PLC) hydrolyze the phosphodiesteric linkages of
the head group of membrane phospholipids. PLDs and PLCs in plants occur in different …

The biogenesis of lipid droplets (LDs) and the development of adipocytes are two key
aspects of mammalian fat storage. SEIPIN, an integral membrane protein of the endoplasmic …

Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …

Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique
biophysical properties: a small headgroup; negative charge; and a phosphomonoester …

Lipid droplets (LDs) are multi-functional cellular organelles that store energy, and regulate
many aspects of cell physiology. However, our understanding of the biogenesis of LDs …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Phosphatidic acid (PA) is an essential phospholipid involved in membrane biosynthesis and
signal transduction in all eukaryotes. This review focuses on its role as lipid second …