As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol
and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of …

Intracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke
worldwide and confers one of the greatest risks of recurrent stroke compared with other …

Large vessel occlusion stroke due to underlying intracranial atherosclerotic disease (ICAD-
LVO) is prevalent in 10 to 30% of LVOs depending on patient factors such as vascular risk …

The aim of the present European Stroke Organisation guideline is to provide clinically useful
evidence-based recommendations on the management of patients with intracranial …

Statins, known as HMG-CoA reductase (HMGCR) inhibitors, have primarily been utilized for
metabolic and angiographic medical applications because of their cholesterol-lowering …

Novel imaging techniques and biomarkers have emerged as surrogate markers of carotid
plaque vulnerability. In parallel, statin administration in patients with established carotid …

Identifying the cerebral arterial branches is essential for undertaking a computational
approach to cerebrovascular imaging. However, the complexity and inter-individual …

Introduction Intracranial atherosclerotic stenosis (ICAS) is a common cause of stroke
worldwide. Evolocumab, a proprotein convertase subtilisin/kexin type-9 inhibitor (PCSK9i) …

Background and purpose Dyslipidaemia is a major risk factor for ischaemic stroke and
transient ischaemic attack (TIA). This study aimed to investigate the association between …

Hyperlipidemia is an important risk factor for ischemic stroke; the Stroke Prevention by
Aggressive Reduction in Cholesterol Level and Treat Stroke to Target studies have shown …