Function and mechanisms of enteroendocrine cells and gut hormones in metabolism
FM Gribble, F Reimann - Nature Reviews Endocrinology, 2019 - nature.com
Gut hormones have many key roles in the control of metabolism, as they target diverse
tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation …
tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation …
Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …
management of obesity and type 2 diabetes mellitus and novel developments in …
Normal and disordered gastric emptying in diabetes: recent insights into (patho) physiology, management and impact on glycaemic control
Gastric emptying is a major determinant of postprandial blood glucose, accounting for~ 35%
of variance in peak glucose in both healthy individuals and those with type 2 diabetes …
of variance in peak glucose in both healthy individuals and those with type 2 diabetes …
Metformin alters upper small intestinal microbiota that impact a glucose-SGLT1-sensing glucoregulatory pathway
The gut microbiota alters energy homeostasis. In parallel, metformin regulates upper small
intestinal sodium glucose cotransporter-1 (SGLT1), but whether changes of the microbiota or …
intestinal sodium glucose cotransporter-1 (SGLT1), but whether changes of the microbiota or …
Relationships between gastric emptying, postprandial glycemia, and incretin hormones
The importance of achieving tight glycemic control, usually assessed by glycated
hemoglobin (HbA1c), for both the prevention and delay in the progression of diabetes …
hemoglobin (HbA1c), for both the prevention and delay in the progression of diabetes …
Gastric emptying and glycaemia in health and diabetes mellitus
The rate of gastric emptying is a critical determinant of postprandial glycaemia and,
accordingly, is fundamental to maintaining blood glucose homeostasis. Disordered gastric …
accordingly, is fundamental to maintaining blood glucose homeostasis. Disordered gastric …
Ageing is associated with decreases in appetite and energy intake—a meta-analysis in healthy adults
It is not well recognized that in the elderly weight loss is more common than weight gain. The
aim of this analysis was to determine the effect of ageing on appetite (hunger/fullness) and …
aim of this analysis was to determine the effect of ageing on appetite (hunger/fullness) and …
The L-cell in nutritional sensing and the regulation of appetite
E Spreckley, KG Murphy - Frontiers in nutrition, 2015 - frontiersin.org
The gastrointestinal (GI) tract senses the ingestion of food and responds by signaling to the
brain to promote satiation and satiety. Representing an important part of the gut–brain axis …
brain to promote satiation and satiety. Representing an important part of the gut–brain axis …
Dietary fibre for glycaemia control: Towards a mechanistic understanding
HD Goff, N Repin, H Fabek, D El Khoury… - … and dietary fibre, 2018 - Elsevier
One of the many functional benefits of dietary fibre when present in the human diet is its
ability to reduce the rate of absorption of glucose after consumption of high glycaemic …
ability to reduce the rate of absorption of glucose after consumption of high glycaemic …
Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects
J Ma, M Bellon, JM Wishart, R Young… - American Journal …, 2009 - journals.physiology.org
The incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP), play an important role in glucose homeostasis in both …
insulinotropic polypeptide (GIP), play an important role in glucose homeostasis in both …