Supramolecular Chemotherapy with Cucurbit[n]urils as Encapsulating Hosts
S Shukla, B Sagar, AK Sood, A Gaur… - ACS Applied Bio …, 2023 - ACS Publications
The cucurbit [n] urils (CB [n]) belong to the field of relatively young supramolecules which act
as containers for a large variety of guests and are being explored extensively for their …
as containers for a large variety of guests and are being explored extensively for their …
Advances in porphyrins and chlorins associated with polysaccharides and polysaccharides-based materials for biomedical and pharmaceutical applications
RFN Quadrado, S Silvestri, JF de Souza… - Carbohydrate …, 2024 - Elsevier
Over the last decade, the convergence of advanced materials and innovative applications
has fostered notable scientific progress within the biomedical and pharmaceutical fields …
has fostered notable scientific progress within the biomedical and pharmaceutical fields …
Acyclic cucurbit [n] uril-based nanosponges significantly enhance the photodynamic therapeutic efficacy of temoporfin in vitro and in vivo
Z Zhao, J Yang, Y Liu, S Wang, W Zhou, ZT Li… - Journal of Materials …, 2023 - pubs.rsc.org
Acyclic cucurbit [n] uril-based nanosponges are prepared based on supramolecular vesicle-
templated cross-linking. The nanosponges are capable of encapsulating the clinically …
templated cross-linking. The nanosponges are capable of encapsulating the clinically …
Deliver on a Promise: Hydrogen-Bonded Polymer Nanomedicine with a Precise Ratio of Chemodrug and Photosensitizer for Intelligent Cancer Therapy
Y Wu, S Chen, J Zhu - ACS nano, 2024 - ACS Publications
The outcomes of combined cancer therapy are largely related to loading content and
contribution of each therapeutic agent; however, fine-tuning the ratio of two coloaded …
contribution of each therapeutic agent; however, fine-tuning the ratio of two coloaded …
[HTML][HTML] Dual-responsive supramolecular photodynamic nanomedicine with activatable immunomodulation for enhanced antitumor therapy
S He, L Wang, D Wu, F Tong, H Zhao, H Li… - … Pharmaceutica Sinica B, 2024 - Elsevier
A major challenge facing photodynamic therapy (PDT) is that the activity of the immune-
induced infiltrating CD8+ T cells is subject to the regulatory T lymphocytes (Tregs), leaving …
induced infiltrating CD8+ T cells is subject to the regulatory T lymphocytes (Tregs), leaving …
pH-responsive dual-drug nanomicelles for co-delivery of DOX and Ce6 for combination therapy of tumors
M Liu, J Lei, K Yuan, Y Zhao, J Zhang, D Li… - Journal of Drug Delivery …, 2023 - Elsevier
In this study, pH-responsive nanomicelles were constructed to co-deliver the
chemotherapeutic drug doxorubicin (DOX) and the photosensitizer chlorin e6 (Ce6). The …
chemotherapeutic drug doxorubicin (DOX) and the photosensitizer chlorin e6 (Ce6). The …
Supramolecular 3 in 1: A Lubrication and Co-Delivery System for Synergistic Advanced Osteoarthritis Therapy
MM Chen, Y Li, Y Zhu, WC Geng, FY Chen, JJ Li… - ACS …, 2024 - ACS Publications
The complexity, heterogeneity, and drug resistance of diseases necessitate a shift in
therapeutic paradigms from monotherapy to combination therapy, which could augment …
therapeutic paradigms from monotherapy to combination therapy, which could augment …
Self-Delivery Nanomedicines Reverse Thermal Resistance to Enhance Tumor Mild-Temperature Photothermal Therapy
J Lai, Q Shi, Y Xie, Y Zhu, S Liang, Y Chen… - Molecular …, 2024 - ACS Publications
Tumoral thermal defense mechanisms considerably attenuate the therapeutic outcomes of
mild-temperature photothermal therapy (PTT). Thus, developing a simple, efficient, and …
mild-temperature photothermal therapy (PTT). Thus, developing a simple, efficient, and …
[HTML][HTML] Dexamethasone-loaded ROS stimuli-responsive nanogels for topical ocular therapy of corneal neovascularization
Y Xiang, Z Qiu, Y Ding, M Du, N Gao, H Cao… - Journal of Controlled …, 2024 - Elsevier
Dexamethasone (DEX) has been demonstrated to inhibit the inflammatory corneal
neovascularization (CNV). However, the therapeutic efficacy of DEX is limited by the poor …
neovascularization (CNV). However, the therapeutic efficacy of DEX is limited by the poor …
Targeted codelivery of doxorubicin and oleanolic acid by reduction responsive hyaluronic acid-based prodrug nano-micelles for enhanced antitumor activity and …
F Kong, H Liu, C Zhao, J Qin - International Journal of Biological …, 2024 - Elsevier
Chemotherapy remains one of the most commonly used strategies in cancer treatment but
suffers from damages to healthy tissues and organs. How to precisely co-deliver two or more …
suffers from damages to healthy tissues and organs. How to precisely co-deliver two or more …