Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination

T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow

R Aguilar, A Magallon-Tejada… - Blood, the journal of …, 2014 - ashpublications.org
Plasmodium falciparum immature gametocytes are not observed in peripheral blood.
However, gametocyte stages in organs such as bone marrow have never been assessed by …

Seasonal variations in Plasmodium falciparum parasite prevalence assessed by varying diagnostic tests in asymptomatic children in southern Ghana

R Ayanful-Torgby, NB Quashie, JN Boampong… - PloS one, 2018 - journals.plos.org
Plasmodium falciparum infections presenting either as symptomatic or asymptomatic may
contain sexual stage parasites (gametocytes) that are crucial to malaria transmission. In this …

A sub-microscopic gametocyte reservoir can sustain malaria transmission

S Karl, D Gurarie, PA Zimmerman, CH King… - PloS one, 2011 - journals.plos.org
Background Novel diagnostic tools, including PCR and high field gradient magnetic
fractionation (HFGMF), have improved detection of asexual Plasmodium falciparum …

Molecular diagnosis of infections and resistance in veterinary and human parasites

PW Hunt - Veterinary Parasitology, 2011 - Elsevier
Since 1977,> 2000 research papers described attempts to detect, identify and/or quantify
parasites, or disease organisms carried by ecto-parasites, using DNA-based tests and 148 …

[HTML][HTML] Polymerase chain reaction-based malaria diagnosis can be increasingly adopted during current phase of malaria elimination in India

M Rahi, R Sharma, P Saroha… - The American Journal …, 2022 - ncbi.nlm.nih.gov
Despite commendable progress in control of malaria in India and other countries, there are
hidden reservoirs of parasites in human hosts that continually feed malaria transmission …

Magneto-optical diagnosis of symptomatic malaria in Papua New Guinea

L Arndt, T Koleala, Á Orbán, C Ibam, E Lufele… - Nature …, 2021 - nature.com
Improved methods for malaria diagnosis are urgently needed. Here, we evaluate a novel
method named rotating-crystal magneto-optical detection (RMOD) in 956 suspected malaria …

Optimization of a Membrane Feeding Assay for Plasmodium vivax Infection in Anopheles albimanus

AF Vallejo, K Rubiano, A Amado… - PLoS neglected …, 2016 - journals.plos.org
Introduction Individuals exposed to malaria infections for a long time develop immune
responses capable of blocking Plasmodium transmission to mosquito vectors, potentially …

Design of microfluidic channels for magnetic separation of malaria-infected red blood cells

WT Wu, AB Martin, A Gandini, N Aubry… - Microfluidics and …, 2016 - Springer
This study is motivated by the development of a blood cell filtration device for removal of
malaria-infected, parasitized red blood cells (pRBCs). The blood was modeled as a multi …

[HTML][HTML] Plasmodium falciparum gametocyte enrichment in peripheral blood samples by magnetic fractionation: gametocyte yields and possibilities to reuse columns

W Graumans, C Andolina, SS Awandu… - The American journal …, 2019 - ncbi.nlm.nih.gov
Gametocytes are sexual stage malaria parasites responsible for transmission to mosquitoes.
Multiple gametocyte-producing clones may be present in natural infections, but the …