[HTML][HTML] Biomarkers of chondrocyte apoptosis and autophagy in osteoarthritis
G Musumeci, P Castrogiovanni, FM Trovato… - International journal of …, 2015 - mdpi.com
Cell death with morphological and molecular features of apoptosis has been detected in
osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte death/survival in the …
osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte death/survival in the …
[HTML][HTML] NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis
JA Roman-Blas, SA Jimenez - Osteoarthritis and cartilage, 2006 - Elsevier
The family of nuclear factor-kappaB (NF-κB) transcription factors is intimately involved in the
regulation of expression of numerous genes in the setting of the inflammatory response …
regulation of expression of numerous genes in the setting of the inflammatory response …
[HTML][HTML] Mitochondria and reactive oxygen species: physiology and pathophysiology
S Bolisetty, EA Jaimes - International journal of molecular sciences, 2013 - mdpi.com
The air that we breathe contains nearly 21% oxygen, most of which is utilized by
mitochondria during respiration. While we cannot live without it, it was perceived as a bane …
mitochondria during respiration. While we cannot live without it, it was perceived as a bane …
[HTML][HTML] Targeting nuclear factor-kappa B to overcome resistance to chemotherapy
Intrinsic or acquired resistance to chemotherapeutic agents is a common phenomenon and
a major challenge in the treatment of cancer patients. Chemoresistance is defined by a …
a major challenge in the treatment of cancer patients. Chemoresistance is defined by a …
To be, or not to be: NF-κB is the answer–role of Rel/NF-κB in the regulation of apoptosis
J Kucharczak, MJ Simmons, Y Fan, C Gelinas - Oncogene, 2003 - nature.com
During their lifetime, cells encounter many life or death situations that challenge their very
own existence. Their survival depends on the interplay within a complex yet precisely …
own existence. Their survival depends on the interplay within a complex yet precisely …
[HTML][HTML] Nitric oxide: NO apoptosis or turning it ON?
B Brüne - Cell Death & Differentiation, 2003 - nature.com
Nitric oxide (NO) is known for its diverse activities throughout biology. Among signaling
qualities, NO affects cellular decisions of life and death either by turning on apoptotic …
qualities, NO affects cellular decisions of life and death either by turning on apoptotic …
Current insights into the regulation of programmed cell death by NF-κB
J Dutta, Y Fan, N Gupta, G Fan, C Gelinas - Oncogene, 2006 - nature.com
The nuclear factor-kappaB (NF-κB) transcription factors have emerged as major regulators
of programmed cell death (PCD) whether via apoptosis or necrosis. In this context, NF-κB's …
of programmed cell death (PCD) whether via apoptosis or necrosis. In this context, NF-κB's …
The functional interactions between the MAPK and p53 signaling pathways
GS Wu - Cancer biology & therapy, 2004 - Taylor & Francis
The p53 tumor suppressor protein exerts its growth inhibitory activity by activating and
interacting with diverse signaling pathways. As a downstream target, p53 protein is …
interacting with diverse signaling pathways. As a downstream target, p53 protein is …
[HTML][HTML] Cell death in cartilage
Cell death in cartilage - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals &
Books Search RegisterSign in View PDF Download full issue Search ScienceDirect Elsevier …
Books Search RegisterSign in View PDF Download full issue Search ScienceDirect Elsevier …
The role of Cdc25A in the regulation of cell proliferation and apoptosis
Cell division cycle 25 A (Cdc25A), a dual-specificity protein phosphatase, is one of the most
crucial cell cycle regulators, which removes the inhibitory phosphorylation in cyclin …
crucial cell cycle regulators, which removes the inhibitory phosphorylation in cyclin …