Periodontitis is a disease characterized by tooth‐associated microbial biofilms that drive
chronic inflammation and destruction of periodontal‐supporting tissues. In some individuals …

Periodontitis is characterized by irreversible destruction of periodontal tissue. At present, the
accepted etiology of periodontitis is based on a three-factor theory including pathogenic …

Background: Periodontitis is a chronic inflammatory disease involving an interplay between
bacteria, inflammation, host response genes, and environmental factors. The manifestation …

Pulmonary arterial hypertension (PAH) is a severe progressive disease that may cause early
right ventricular failure and eventual cardiac failure. The pathogenesis of PAH involves …

Objective The objective of the study was to profile the expression level of histone
deacetylase enzymes (HDACs) in human saliva in periodontal health, gingivitis and …

Background The aim of this study was to investigate the association between periodontitis
and four single nucleotide polymorphisms (SNPs) in genes involved in epigenetic regulation …

Bone tissue engineering is a complicated field requiring concerted participation of cells,
scaffolds, and osteoactive molecules to replace damaged bone. This study synthesized a …

Periodontal disease, one of the most prevalent human infectious diseases, is characterized
by chronic inflammatory tissue destruction of the alveolar bone and the connective tissues …

Aim To evaluate the effect of non‐surgical periodontal therapy (NSPT) on salivary histone
deacetylases (HDACs) gene expression in patients with Stage III–IV periodontitis at baseline …

Abstract Background The Encyclopedia of DNA Elements (ENCODE) project has advanced
our knowledge of the functional elements in the genome and epigenome. The aim of this …