Antibody therapy is effective for treating infectious diseases. Due to the coronavirus disease
2019 (COVID-19) pandemic and the rise of drug-resistant bacteria, rapid development of …

Botulinum neurotoxin (BoNT) is produced by the anaerobic, Gram-positive bacterium
Clostridium botulinum. As one of the most poisonous toxins known and a potential …

Background Botulinum neurotoxin (BoNT) produced by Clostridium botulinum is one of the
most potent known toxins. Moreover, BoNT is classified as one of the most important …

ABSTRACT Introduction: Botulinum neurotoxins (BoNTs) are the most potent toxins known.
BoNTs are responsible for botulism, a deadly neuroparalytic syndrome caused by the …

Human botulism is most commonly caused by botulinum neurotoxin (BoNT) serotypes A, B,
and E. For this work, we sought to develop a human monoclonal antibody (mAb)-based …

Human botulism is primarily caused by botulinum neurotoxin (BoNT) serotypes A, B and E,
with around 1% caused by serotype F (BoNT/F). BoNT/F comprises at least seven different …

Botulinum neurotoxin (BoNT) is a highly potent and lethal toxin, which even in minute
quantities can lead to death. BoNT occurs in seven well described serotypes, AG, and it is …

Botulism is caused by botulinum neurotoxin (BoNT), the most poisonous substance known.
BoNTs are also classified as tier 1 biothreat agents due to their high potency and lethality …

Equine-derived antitoxin (BAT®) is the only treatment for botulism from botulinum neurotoxin
serotype G (BoNT/G). BAT® is a foreign protein with potentially severe adverse effects and is …

Botulinum neurotoxins (BoNT) are extremely potent and can induce respiratory failure,
requiring long-term intensive care to prevent death. Recombinant monoclonal antibodies …