Stress-induced changes in the immune system, which lead to neuroinflammation and
consequent brain alterations, have been suggested as possible neurobiological substrates …

Generalized anxiety disorder (GAD) is characterized by excessive worry about a variety of
topics. In addition to the presence of uncontrollable and persistent worry, the diagnosis of …

Objective To compare structure, functional connectivity (FC) and task-based neural
differences in subjects with generalized anxiety disorder (GAD) compared to healthy …

Background Heart rate variability (HRV) in patients with emotional disorders and healthy
controls (HCs) has been investigated in many studies but the difference between these …

The goal of this study was to compare brain structure between individuals with generalized
anxiety disorder (GAD) and healthy controls. Previous studies have generated inconsistent …

Adolescence is the peak period for the incidence of anxiety disorders. Recent findings have
revealed the immaturity of neural networks underlying emotional regulation in this …

Background Research on the neurobiological basis of Generalized Anxiety Disorder (GAD)
has considerably expanded in recent years. However, many studies investigated different …

Objectives: Brain imaging studies carried out in patients suffering from generalized anxiety
disorder (GAD) have contributed to better characterize the pathophysiological mechanisms …

The hypothalamus is critical for regulation of the hypothalamic-pituitary-adrenal (HPA) axis
and response to stress. Adverse childhood experience (ACE) can affect brain structure …

Anxiety disorders are frequently encountered in the elderly, but they are largely undetected
and untreated. Epidemiological studies indicate a prevalence ranging from 1.2 to 15%. With …