Triglyceride molecules represent the major form of storage and transport of fatty acids within
cells and in the plasma. The liver is the central organ for fatty acid metabolism. Fatty acids …

Abstract The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription
factor that plays a major role in metabolic regulation. This review addresses the functional …

White adipocytes store excess energy in the form of triglycerides, whereas brown and beige
adipocytes dissipate energy in the form of heat. This thermogenic function relies on the …

Brown adipose tissue dissipates energy through heat and functions as a defense against
cold and obesity. PPARγ ligands have been shown to induce the browning of white …

The peroxisome proliferator‐activated receptor alpha (PPARα) is a ligand‐activated
transcription factor involved in the regulation of a variety of processes, ranging from …

Peroxisome proliferator-activated receptors (PPARs) are nuclear proteins that belong to the
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …

Storage of energy as triglyceride in large adipose-specific lipid droplets is a fundamental
need in all mammals. Efficient sequestration of fat in adipocytes also prevents fatty acid …

Peroxisome proliferator-activated receptor γ (PPARγ) is induced in leptin-deficient (ob/ob)
mouse liver and is critical for the development of hepatic steatosis. The present study shows …

The morphological and functional differences between lipid droplets (LDs) in brown (BAT)
and white (WAT) adipose tissues will largely be determined by their associated proteins …

In contrast to the earlier contention, adult humans have been shown recently to possess
active brown adipose tissue with a potential of being of metabolic significance. Up to now …