Human diseases have always been a significant turf of concern since the origin of mankind.
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …

In mammals, the vast majority of transcripts expressed are noncoding RNAs, ranging from
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …

A goal of human genetics studies is to determine the mechanisms by which genetic variation
produces phenotypic differences that affect human health. Efforts in this respect have …

The ribosome, central to protein synthesis in all cells, is a complex multicomponent
assembly with rRNA at its functional core. During the process of ribosome biogenesis …

The rapid development of new generation sequencing technology has deepened the
understanding of genomes and functional products. RNA-sequencing studies in mammals …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

RNA polymerase (Pol) III is responsible for transcription of different noncoding genes in
eukaryotic cells, whose RNA products have well-defined functions in translation and other …

Non-coding RNA (ncRNA) molecules have fundamental roles in cells and many are also
stable in body fluids as extracellular RNAs. In this study, we used RNA sequencing (RNA …

Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis. However, the
mechanisms of most lncRNAs in cancers are largely unknown. Because the RNA …