Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia
S Beneyto-Calabuig, AK Merbach, JA Kniffka, M Antes… - Cell Stem Cell, 2023 - cell.com
Inter-patient variability and the similarity of healthy and leukemic stem cells (LSCs) have
impeded the characterization of LSCs in acute myeloid leukemia (AML) and their …
impeded the characterization of LSCs in acute myeloid leukemia (AML) and their …
Minority report: the intestinal mycobiota in systemic infections
Highlights•The human mycobiota contains clinically relevant fungal species.•Longitudinal
sampling provides robust insights into the human mycobiota.•Simultaneous analysis of …
sampling provides robust insights into the human mycobiota.•Simultaneous analysis of …
A rapid, cost-effective tailed amplicon method for sequencing SARS-CoV-2
Background The global COVID-19 pandemic has led to an urgent need for scalable
methods for clinical diagnostics and viral tracking. Next generation sequencing technologies …
methods for clinical diagnostics and viral tracking. Next generation sequencing technologies …
Quantification, dynamic visualization, and validation of bias in ATAC-seq data with ataqv
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) has become
the preferred method for mapping chromatin accessibility due to its time and input material …
the preferred method for mapping chromatin accessibility due to its time and input material …
Adapterama II: universal amplicon sequencing on Illumina platforms (TaggiMatrix)
Next-generation sequencing (NGS) of amplicons is used in a wide variety of contexts. In
many cases, NGS amplicon sequencing remains overly expensive and inflexible, with library …
many cases, NGS amplicon sequencing remains overly expensive and inflexible, with library …
Pitfalls and pointers: an accessible guide to marker gene amplicon sequencing in ecological applications
A Porath‐Krause, AT Strauss… - Methods in Ecology …, 2022 - Wiley Online Library
Abstract Next‐Generation Sequencing (NGS) is a powerful tool that has been rapidly
adopted by many ecologists studying microbial communities. Despite the exciting …
adopted by many ecologists studying microbial communities. Despite the exciting …
Sequencing Illumina libraries at high accuracy on the ONT MinION using R2C2
High-throughput short-read sequencing has taken on a central role in research and
diagnostics. Hundreds of different assays take advantage of Illumina short-read sequencers …
diagnostics. Hundreds of different assays take advantage of Illumina short-read sequencers …
Genome sequence variations of infectious bronchitis virus serotypes from commercial chickens in Mexico
HM Kariithi, JD Volkening, CM Leyson… - Frontiers in Veterinary …, 2022 - frontiersin.org
New variants of infectious bronchitis viruses (IBVs; Coronaviridae) continuously emerge
despite routine vaccinations. Here, we report genome sequence variations of IBVs identified …
despite routine vaccinations. Here, we report genome sequence variations of IBVs identified …
Plant DNA barcoding necessitates marker-specific efforts to establish more comprehensive reference databases
A Kolter, B Gemeinholzer - Genome, 2021 - cdnsciencepub.com
The problem of low species-level identification rates in plants by DNA barcoding is
exacerbated by the fact that reference databases are far from being comprehensive. We …
exacerbated by the fact that reference databases are far from being comprehensive. We …
Combining TSS-MPRA and sensitive TSS profile dissimilarity scoring to study the sequence determinants of transcription initiation
C Guzman, S Duttke, Y Zhu… - Nucleic Acids …, 2023 - academic.oup.com
Cis-regulatory elements (CREs) can be classified by the shapes of their transcription start
site (TSS) profiles, which are indicative of distinct regulatory mechanisms. Massively parallel …
site (TSS) profiles, which are indicative of distinct regulatory mechanisms. Massively parallel …