[HTML][HTML] Preclinical in vivo-models to investigate HIPEC; current methodologies and challenges

RF Helderman, DR Löke, PJ Tanis, JB Tuynman… - Cancers, 2021 - mdpi.com
Simple Summary Efficacy of cytoreductive surgery (CRS) combined with hyperthermic
intraperitoneal chemotherapy (HIPEC) depends on patient selection, tumor type, delivery …

[HTML][HTML] Experimental models of high-risk bowel anastomosis in rats: A systematic review

G Ntampakis, MG Pramateftakis… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Anastomotic leaks remain one of the most dreaded complications in
gastrointestinal surgery causing significant morbidity, that negatively affect the patients' …

[HTML][HTML] Platelet-rich plasma treatment improves postoperative recovery in patients with pilonidal sinus disease: a randomized controlled clinical trial

CY Boztug, T Karaagac Akyol, C Benlice, MA Koc… - BMC surgery, 2021 - Springer
Background Pilonidal sinus is a common health problem. The current study aimed to
compare the impact of autologous platelet-rich plasma (PRP) with that of minimally invasive …

[HTML][HTML] The influence of platelet-rich plasma (PRP) on colonic anastomosis healing impaired by intraperitoneal 5-flourouracil application. An experimental study

M Gorur, A Sozutek, O Irkorucu… - Acta Cirúrgica Brasileira, 2020 - SciELO Brasil
Abstract Purpose 5-flourourasil (5-FU) is commonly used for early intraperitoneal
chemotherapy in colorectal or appendiceal cancer patients with peritoneal carcinomatosis …

[HTML][HTML] Platelet rich plasma effectiveness in bowel anastomoses: A systematic review

G Geropoulos, K Psarras, D Giannis… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Anastomotic leak constitutes a major problem in abdominal surgery.
Technical insufficiency, topical or systemic factors contribute to disrupted healing of the …

[PDF][PDF] Biochemical and haematological profiles, gross and histopathological lesions associated with the parenteral administration of fixed dose of ketamine in albino …

BI Joshua, IL Elisha, AC Faith, BD Jummai… - Journal of Drugs and …, 2023 - researchgate.net
The study examined the impact of different routes of administration of ketamine on various
parameters in albino rats. Nine healthy adult rats with an average weight of 170 g were …

The protective effect of sildenafil on colon anastomosis in a rat model undergoing hypertermic intraperitoneal chemotherapy

A Başak, MT Aydın, MM Fersahoğlu, İ Taşdelen… - 2024 - researchsquare.com
Aim: The aim of the study is to investigate the effects of sildenafil on colonic anastomosis
healing in rats treated with hyperthermic intraperitoneal chemotherapy. Method: In our study …