Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …

Sesamol is a lignan of sesame seeds and a natural phenolic molecule that has emerged as
a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain …

Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low
perfusion of the drug to the brain. The objective of the current investigation was to design …

The objective of this work was to optimize a thermosensitive in situ gelling formulation to
improve intranasal and nose-to-brain delivery of the antiepileptic drug carbamazepine …

Migraine is a progressive neurological condition often accompanied by nausea and
vomiting. Various drugs have recently been used in the treatment of migraine, including …

Alzheimer-type dementia (ATD) treatments face limitations in crossing the blood–brain
barrier and systemic adverse effects. Intranasal administration offers a direct route to the …

Fluorescent organic nanoparticles (FONs) are a large family of nanostructures constituted by
organic components that emit light in different spectral regions upon excitation, due to the …

Alzheimer's disease (AD) is the most common form of dementia, with a high impact
worldwide, accounting for more than 46 million cases. The continuous increase of AD …