Frailty in older adults
DH Kim, K Rockwood - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Frailty in Older Adults Assessing frailty enables clinicians to predict the outcomes
and risks of health conditions, target the delivery of evidence-based interventions, and tailor …
and risks of health conditions, target the delivery of evidence-based interventions, and tailor …
Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies
R O'Caoimh, D Sezgin, MR O'Donovan… - Age and …, 2021 - academic.oup.com
Introduction The prevalence of frailty at population level is unclear. We examined this in
population-based studies, investigating sources of heterogeneity. Methods PubMed …
population-based studies, investigating sources of heterogeneity. Methods PubMed …
The degree of frailty as a translational measure of health in aging
Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …
outcomes. We review how the degree of frailty conditions the development of late-life …
Multisystem physiological perspective of human frailty and its modulation by physical activity
JA Taylor, PL Greenhaff, DB Bartlett… - Physiological …, 2023 - journals.physiology.org
“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank participants
Background Frailty is associated with older age and multimorbidity (two or more long-term
conditions); however, little is known about its prevalence or effects on mortality in younger …
conditions); however, little is known about its prevalence or effects on mortality in younger …
The continuum of aging and age-related diseases: common mechanisms but different rates
Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …
ESPEN guidelines on definitions and terminology of clinical nutrition
T Cederholm, R Barazzoni, P Austin, P Ballmer, G Biolo… - Clinical nutrition, 2017 - Elsevier
Background A lack of agreement on definitions and terminology used for nutrition-related
concepts and procedures limits the development of clinical nutrition practice and research …
concepts and procedures limits the development of clinical nutrition practice and research …
[HTML][HTML] Inflammation and frailty in the elderly: a systematic review and meta-analysis
The pathogenesis of frailty and the role of inflammation is poorly understood. We examined
the evidence considering the relationship between inflammation and frailty through a …
the evidence considering the relationship between inflammation and frailty through a …
Frailty measurement in research and clinical practice: a review
One of the leading causes of morbidity and premature mortality in older people is frailty.
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …
Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and meta-analysis
DD Siriwardhana, S Hardoon, G Rait… - BMJ open, 2018 - bmjopen.bmj.com
Objective To systematically review the research conducted on prevalence of frailty and
prefrailty among community-dwelling older adults in low-income and middle-income …
prefrailty among community-dwelling older adults in low-income and middle-income …