Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers

A Sosnik, KP Seremeta - Advances in colloid and interface science, 2015 - Elsevier
Spray-drying is a rapid, continuous, cost-effective, reproducible and scalable process for the
production of dry powders from a fluid material by atomization through an atomizer into a hot …

[HTML][HTML] Nanoparticle-mediated pulmonary drug delivery: a review

M Paranjpe, CC Müller-Goymann - International journal of molecular …, 2014 - mdpi.com
Colloidal drug delivery systems have been extensively investigated as drug carriers for the
application of different drugs via different routes of administration. Systems, such as solid …

[HTML][HTML] Technological and practical challenges of dry powder inhalers and formulations

M Hoppentocht, P Hagedoorn, HW Frijlink… - Advanced drug delivery …, 2014 - Elsevier
In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …

[图书][B] Handbook of encapsulation and controlled release

M Mishra - 2015 - books.google.com
Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

[HTML][HTML] Inhalable nanoparticulate powders for respiratory delivery

P Muralidharan, M Malapit, E Mallory… - … , Biology and Medicine, 2015 - Elsevier
Nanoparticles are extensively studied for drug delivery and are proving to be effective in
drug delivery and the diagnostic field. Drug delivery to lungs has its advantages over other …

[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties

N Alhajj, NJ O'Reilly, H Cathcart - Powder Technology, 2021 - Elsevier
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …

Amorphous powders for inhalation drug delivery

L Chen, T Okuda, XY Lu, HK Chan - Advanced drug delivery reviews, 2016 - Elsevier
For inhalation drug delivery, amorphous powder formulations offer the benefits of increased
bioavailability for poorly soluble drugs, improved biochemical stability for biologics, and …

A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications

HI Shahin, L Chablani - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

Advances in the development of antimicrobial peptides and proteins for inhaled therapy

Y Wang, RYK Chang, WJ Britton, HK Chan - Advanced Drug Delivery …, 2022 - Elsevier
Antimicrobial peptides and proteins (APPs) are becoming increasingly important in targeting
multidrug-resistant (MDR) bacteria. APPs is a rapidly emerging area with novel molecules …

[HTML][HTML] Novel formulations for antimicrobial peptides

AM Carmona-Ribeiro, LDM Carrasco - International journal of molecular …, 2014 - mdpi.com
Peptides in general hold much promise as a major ingredient in novel supramolecular
assemblies. They may become essential in vaccine design, antimicrobial chemotherapy …