It is extremely challenging to chemically diagnose disorders of the brain. There is hence
great interest in designing and optimizing tools for direct detection of chemical biomarkers …

Functional synapses in the central nervous system depend on a chemical signal exchange
process that involves neurotransmitter delivery between neurons and receptor cells in the …

Real-time monitoring of various neurochemicals with high spatial resolution in multiple brain
regions in vivo can elucidate neural circuits related to various brain diseases. However …

Simultaneous detection of spike firing and neurotransmitters in mice is conducive to further
understanding the mechanism of innate fear induced by aversive stimuli. As the key brain …

Glutamate excitotoxicity is a pathology in which excessive glutamate can cause neuronal
damage and degeneration. It has also been linked to secondary injury mechanisms in …

Miniaturized electrochemical in vivo biosensors allow the measurement of fast extracellular
dynamics of neurotransmitter and energy metabolism directly in the tissue. Enzyme-based …

Neural interfaces have enabled significant advancements in neuroscience and paved the
way for clinical applications in the diagnosis, treatment, and prevention of neurological …

Due to the rapid development of micro/nano manufacturing techniques and the greater
understanding in electrochemical principles and methods, micro/nano electrode array …

We present a flexible microsensor, based on a polymer substrate, for multiparametric,
electrochemical in vivo monitoring. The sensor strip with a microelectrode array at the tip …

A polymer/enzyme composite biosensor for monitoring neurochemical glutamate was
performance optimised in vitro for sensitivity, selectivity and stability. This first generation …