Mpox multi-antigen mRNA vaccine candidates by a simplified manufacturing strategy afford efficient protection against lethal orthopoxvirus challenge
J Zeng, Y Li, L Jiang, L Luo, Y Wang… - Emerging microbes & …, 2023 - Taylor & Francis
Current unprecedented mpox outbreaks in non-endemic regions represent a global public
health concern. Although two live-attenuated vaccinia virus (VACV)-based vaccines have …
health concern. Although two live-attenuated vaccinia virus (VACV)-based vaccines have …
A literature review on current practices, knowledge, and viewpoints on pentobarbital euthanasia performed by veterinarians and animal remains disposal in the United …
NS Kollias, WJ Hess, CL Johnson… - Journal of the …, 2023 - Am Vet Med Assoc
Sodium pentobarbital and pentobarbital combination products are commonly used by
veterinarians throughout the US for euthanasia of their animal patients. The AVMA …
veterinarians throughout the US for euthanasia of their animal patients. The AVMA …
Antibiotic-induced gut microbiota dysbiosis has a functional impact on purine metabolism
X Liu, L Ke, K Lei, Q Yu, W Zhang, C Li, Z Tian - BMC microbiology, 2023 - Springer
Background Dysbiosis of the gut microbiota is closely linked to hyperuricemia. However, the
effect of the microbiome on uric acid (UA) metabolism remains unclear. This study aimed to …
effect of the microbiome on uric acid (UA) metabolism remains unclear. This study aimed to …
Commonly overlooked factors in biocompatibility studies of neural implants
LS Kumosa - Advanced Science, 2023 - Wiley Online Library
Biocompatibility of cutting‐edge neural implants, surgical tools and techniques, and
therapeutic technologies is a challenging concept that can be easily misjudged. For …
therapeutic technologies is a challenging concept that can be easily misjudged. For …
[HTML][HTML] Temperature-induced Artifacts in Tau Phosphorylation: Implications for Reliable Alzheimer's Disease Research
G Canet, E Rocaboy, F Laliberté… - Experimental …, 2023 - ncbi.nlm.nih.gov
In preclinical research on Alzheimer's disease and related tauopathies, tau phosphorylation
analysis is routinely employed in both cellular and animal models. However, recognizing the …
analysis is routinely employed in both cellular and animal models. However, recognizing the …
Promising drug candidates for the treatment of polycystic ovary syndrome (PCOS) as alternatives to the classical medication metformin
HS Anbar, NY Vahora, H laghman Shah… - European Journal of …, 2023 - Elsevier
Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder that affects women of
reproductive age. It is characterized by abnormal production of androgens, typically present …
reproductive age. It is characterized by abnormal production of androgens, typically present …
Argel's stemmoside C as a novel natural remedy for mice with alcohol-induced gastric ulcer based on its molecular mechanistic pathways
G Nabil, YH Ahmed, O Ahmed, SS Milad… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Solenostemma argel is widely distributed in Africa & Asia
with traditional usage in alleviating abdominal colic, aches, & cramps. This plant is rich in …
with traditional usage in alleviating abdominal colic, aches, & cramps. This plant is rich in …
Knockdown of polypyrimidine tract binding protein facilitates motor function recovery after spinal cord injury
RY Yang, R Chai, JY Pan, JY Bao, PH Xia… - Neural Regeneration …, 2023 - journals.lww.com
After spinal cord injury (SCI), a fibroblast-and microglia-mediated fibrotic scar is formed in
the lesion core, and a glial scar is formed around the fibrotic scar as a result of the activation …
the lesion core, and a glial scar is formed around the fibrotic scar as a result of the activation …
Isolation and culture of neonatal murine primary cardiomyocytes
The cardiomyocyte is the main cell type in the heart responsible for its contractile function.
Culturing primary cardiomyocytes from mammalian sources to study their function remains …
Culturing primary cardiomyocytes from mammalian sources to study their function remains …
Impact of the functional coating of silver nanoparticles on their in vivo performance and biosafety
HM Tawfeek, MA Younis, BN Aldosari… - Drug Development …, 2023 - Taylor & Francis
Objective and significance Silver nanoparticles (AgNPs) have become an interesting
therapeutic modality and drug delivery platform. Herein, we aimed to investigate the impact …
therapeutic modality and drug delivery platform. Herein, we aimed to investigate the impact …