Endogenous and exogenous sources cause free radical-induced DNA damage in living
organisms by a variety of mechanisms. The highly reactive hydroxyl radical reacts with the …

DNA charge transport (CT) chemistry has received considerable attention by scientific
researchers over the past 15 years since our first provocative publication on long-range CT …

Emphasis is placed in the first part of this survey on mechanistic aspects of the formation of 8-
oxo-7, 8-dihydroguanine (8-oxoGua) as the result of exposure to OH radical, one-electron …

Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

The dynamics of photoinduced charge separation and charge recombination processes in
synthetic DNA hairpins have been investigated by means of femtosecond transient …

The chemistry of singlet molecular oxygen [1O2 (1Δg)], its importance in atmospheric,
biological, and therapeutic processes, and its use as a reagent in organic synthesis have …

Use of one-electron oxidants such as Na2IrCl6 to oxidize 8-oxo-7, 8-dihydro-2 '-
deoxyguanosine (OG) residues in oligodeoxynucleotides was previously shown to lead to …

Reactive oxygen species (ROS) are harnessed by the cell for signaling at the same time as
being detrimental to cellular components such as DNA. The genome and transcriptome …

Many, if not all, environmental pollutants/chemicals and infectious agents increase
intracellular levels of reactive oxygen species (ROS) at the site of exposure. ROS not only …

Single-stranded DNA genomes have been constructed that site-specifically contain the 7, 8-
dihydro-8-oxo-2 '-deoxyguanine (8-oxoG) oxidation products guanidinohydantoin (Gh) and …