The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

Nuclear ribonuclease (RNase) P is a ubiquitous essential ribonucleoprotein complex, one of
only two known RNA-based enzymes found in all three domains of life. The RNA component …

Transfer‐RNA (tRNA) molecules are essential players in protein biosynthesis. They are
transcribed as precursors, which have to be extensively processed at both ends to become …

The adjacent gadX and gadW genes encode transcription regulators that are part of a
complex regulatory circuit controlling the Escherichia coli response to acid stress. We …

The replication frequency of plasmid R1 is post‐transcriptionally controlled by an antisense
RNA, CopA, that binds to the leader region in the RepA mRNA, CopT, and ultimately inhibits …

Analysis of crosslinked complexes of M1 RNA, the catalytic RNA subunit of ribonuclease P
from Escherichia coli, and transfer RNA precursor substrates has led to the identification of …

Abstract Ribonuclease P (RNase P), which is required for the 5'‐end maturation of tRNAs in
every organism, has been shown to play a limited role in other aspects of RNA metabolism …

RNase P from Escherichia coli cleaves the coenzyme B12 riboswitch from E. coli and a
similar one from Bacillus subtilis. The cleavage sites do not occur in any recognizable …

Plasmids encoding various external guide sequences (EGSs) were constructed and inserted
into Escherichia coli. In strains harboring the appropriate plasmids, the expression of fully …

Background Mycobacterium avium subspecies avium (M. avium) is frequently encountered
in the environment, but also causes infections in animals and immunocompromised patients …