The RAS-Extracellular signal-regulated kinase (RAS-ERK) pathway plays a conserved role
in promoting cell migration and invasion. Growth factors, adhesion, and oncogenes activate …

Extracellular signal-regulated kinase (ERK) has been recognized as a critical regulator in
various physiological and pathological processes. Extensive research has elucidated the …

It is a big challenge to design a biomimetic physical microenvironment with greater similarity
to in vivo tissue to observe real cell behaviors. We established a novel cell culture platform …

The precise execution of various cellular functions relies on the maintenance of signaling
specificity from input detection to cellular outputs. However, diverse signaling pathways …

Signaling by the extracellular signal-regulated kinase (ERK) pathway controls many cellular
processes, including cell division, death, and differentiation. In this second installment of a …

Simple Summary Prostate cancer is a malignancy that affects a high number of men all over
the world. When indolent, prostate cancer can remain silent for years without needing …

Alveolar type 2 epithelial cells (AT2s) derived from human induced pluripotent stem cells
(iAT2s) have rapidly contributed to our understanding of AT2 function and disease …

Breast cancer is characterized by physical changes that occur in the tumor
microenvironment throughout growth and metastasis of tumors. Extracellular matrix stiffness …

Extracellular signal-regulated kinase (ERK) plays a crucial role in regulating collective cell
behaviors observed in diverse biological phenomena. Emerging studies have shed light on …

Optogenetic tools respond to light through one of a small number of behaviors including
allosteric changes, dimerization, clustering, or membrane translocation. Here, we describe a …