Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination
T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …
falciparum responsible for the majority of the disease burden and P. vivax being the …
Artemisinin resistance: current status and scenarios for containment
AM Dondorp, S Yeung, L White, C Nguon… - Nature Reviews …, 2010 - nature.com
Artemisinin combination therapies are the first-line treatments for uncomplicated
Plasmodium falciparum malaria in most malaria-endemic countries. Recently, partial …
Plasmodium falciparum malaria in most malaria-endemic countries. Recently, partial …
[HTML][HTML] G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map
RE Howes, FB Piel, AP Patil, OA Nyangiri… - PLoS …, 2012 - journals.plos.org
Background Primaquine is a key drug for malaria elimination. In addition to being the only
drug active against the dormant relapsing forms of Plasmodium vivax, primaquine is the sole …
drug active against the dormant relapsing forms of Plasmodium vivax, primaquine is the sole …
Operational strategies to achieve and maintain malaria elimination
Present elimination strategies are based on recommendations derived during the Global
Malaria Eradication Program of the 1960s. However, many countries considering elimination …
Malaria Eradication Program of the 1960s. However, many countries considering elimination …
[HTML][HTML] Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the …
Background There is renewed acknowledgement that targeting gametocytes is essential for
malaria control and elimination efforts. Simple mathematical models were fitted to data from …
malaria control and elimination efforts. Simple mathematical models were fitted to data from …
Predicting mosquito infection from Plasmodium falciparum gametocyte density and estimating the reservoir of infection
Transmission reduction is a key component of global efforts to control and eliminate malaria;
yet, it is unclear how the density of transmission stages (gametocytes) influences infection …
yet, it is unclear how the density of transmission stages (gametocytes) influences infection …
Recasting the theory of mosquito-borne pathogen transmission dynamics and control
Mosquito-borne diseases pose some of the greatest challenges in public health, especially
in tropical and sub-tropical regions of the world. Efforts to control these diseases have been …
in tropical and sub-tropical regions of the world. Efforts to control these diseases have been …
Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission
Background The 8‐aminoquinoline (8AQ) drugs act on Plasmodium falciparum
gametocytes, which transmit malaria from infected people to mosquitoes. In 2012, the World …
gametocytes, which transmit malaria from infected people to mosquitoes. In 2012, the World …
A sticky situation: the unexpected stability of malaria elimination
Malaria eradication involves eliminating malaria from every country where transmission
occurs. Current theory suggests that the post-elimination challenges of remaining malaria …
occurs. Current theory suggests that the post-elimination challenges of remaining malaria …
Ranking of elimination feasibility between malaria-endemic countries
Experience gained from the Global Malaria Eradication Program (1955–72) identified a set
of shared technical and operational factors that enabled some countries to successfully …
of shared technical and operational factors that enabled some countries to successfully …