The evolution of the eye is a matter of debate ever since Darwin's Origin of Species. While
morphological comparisons of eye anatomy and photoreceptor cell types led to the view that …

Current information on the conodonts Clydagnathus windsorensis (Globensky) and
Promissum pulchrum Kovács–Endrödy, together with the latest interpretations of conodont …

Reconstructing the genomes of bilaterian ancestors is central to our understanding of animal
evolution, where knowledge from ancient and/or slow-evolving bilaterian lineages is critical …

It has been hypothesized that a condensed nervous system with a medial ventral nerve cord
is an ancestral character of Bilateria. The presence of similar dorsoventral molecular …

Pax6 is a transcription factor essential for the development of tissues including the eyes,
central nervous system and endocrine glands of vertebrates and invertebrates. It regulates …

Abstract The Drosophila Pax-6 gene eyeless (ey) plays a key role in eye development. Here
we show that Drosophila contains a second Pax-6 gene, twin of eyeless (toy), due to a …

The retina pigment epithelium (RPE) is a highly specialised epithelium that serves as a
multifunctional and indispensable component of the vertebrate eye. Although a great deal of …

The DNA-binding transcription factor PAX6 was cloned 25 years ago by multiple teams
pursuing identification of human and mouse eye disease causing genes, cloning vertebrate …

The question of whether the ancestral bilaterian had a central nervous system (CNS) or a
diffuse ectodermal nervous system has been hotly debated. Considerable evidence …

Müller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of
functional interactions between neurons and Müller cells, including delivery of the light …