Sudden cardiac death in the young: the molecular autopsy and a practical approach to surviving relatives
C Semsarian, J Ingles, AAM Wilde - European heart journal, 2015 - academic.oup.com
The sudden death of a young, apparently fit and healthy person is amongst the most
challenging scenarios in clinical medicine. Sudden cardiac death (SCD) is a devastating …
challenging scenarios in clinical medicine. Sudden cardiac death (SCD) is a devastating …
[HTML][HTML] Molecular autopsy in victims of inherited arrhythmias
C Semsarian, J Ingles - Journal of arrhythmia, 2016 - Elsevier
Sudden cardiac death (SCD) is a rare but devastating complication of a number of
underlying cardiovascular diseases. While coronary artery disease and acute myocardial …
underlying cardiovascular diseases. While coronary artery disease and acute myocardial …
Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance
RE Eckart, EA Shry, AP Burke, JA McNear… - Journal of the American …, 2011 - jacc.org
Objectives: The purpose of this study was to define the incidence and characterization of
cardiovascular cause of sudden death in the young. Background: The epidemiology of …
cardiovascular cause of sudden death in the young. Background: The epidemiology of …
Familial cardiological and targeted genetic evaluation: low yield in sudden unexplained death and high yield in unexplained cardiac arrest syndromes
Background It has been reported that cardiological screening and genetic evaluation in
relatives of families with sudden unexplained death syndrome and unexplained cardiac …
relatives of families with sudden unexplained death syndrome and unexplained cardiac …
Sudden death in the young: what do we know about it and how to prevent?
C Van Der Werf, IM Van Langen… - Circulation: Arrhythmia …, 2010 - Am Heart Assoc
Sudden death (SD) of children and adults ages 1 to 40 years has received increasing
attention over the past decades. In this report, we provide an overview of this problem …
attention over the past decades. In this report, we provide an overview of this problem …
Key role of the molecular autopsy in sudden unexpected death
C Semsarian, RM Hamilton - Heart Rhythm, 2012 - Elsevier
Sudden Cardiac Death (SCD) is a major and tragic complication of a number of
cardiovascular diseases. While in the older populations, SCD is most frequently caused by …
cardiovascular diseases. While in the older populations, SCD is most frequently caused by …
Post-mortem genetic analysis in juvenile cases of sudden cardiac death
O Campuzano, O Sanchez-Molero, C Allegue… - Forensic science …, 2014 - Elsevier
Background The reason behind a sudden death of a young individual remains unknown in
up to 50% of postmortem cases. Pathogenic mutations in genes encoding heart proteins are …
up to 50% of postmortem cases. Pathogenic mutations in genes encoding heart proteins are …
Efficiency evaluation of a DNA extraction and purification protocol on archival formalin-fixed and paraffin-embedded tissue
A Farrugia, C Keyser, B Ludes - Forensic Science International, 2010 - Elsevier
Formalin-fixed and paraffin-embedded tissue (FF-PET) is an invaluable resource for
retrospective molecular genetic studies, but the extraction of high-quality genomic DNA from …
retrospective molecular genetic studies, but the extraction of high-quality genomic DNA from …
[PDF][PDF] Sudden arrhythmia death syndrome in young victims: a five-year retrospective review and two-year prospective molecular autopsy study by next-generation …
CM Mak, NS Mok, HC Shum, WK Siu… - Hong Kong …, 2019 - pdfs.semanticscholar.org
Objective: Sudden arrhythmia death syndrome (SADS) accounts for about 30% of causes of
sudden cardiac death (SCD) in young people. In Hong Kong, there are scarce data on …
sudden cardiac death (SCD) in young people. In Hong Kong, there are scarce data on …
Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration
M Eijgelsheim, ALHJ Aarnoudse… - Human molecular …, 2009 - academic.oup.com
QT-interval prolongation is an electrophysiologic phenomenon associated with sudden
cardiac death. The QT-interval in the general population is∼ 35% heritable. In genome-wide …
cardiac death. The QT-interval in the general population is∼ 35% heritable. In genome-wide …