GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells

S Turkalj, NA Jakobsen, A Groom, M Metzner, SG Riva… - Cell Stem Cell, 2023 - cell.com
Understanding clonal evolution and cancer development requires experimental approaches
for characterizing the consequences of somatic mutations on gene regulation. However, no …

Six novel nsSNPs affect RUNX1 gene may leading to Acute Myeloid Leukemia (AML) using Bioinformatics approach

D Omer, T Ameer, T Alsheikh, A NjmEldin… - bioRxiv, 2023 - biorxiv.org
Background RUNX1 is one of the most frequently mutated genes in human AMLs, most of
RUNX1 mutations in acute myeloid leukemia (AML) are missense or deletion-truncation and …