The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …

The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Stress inevitably occurs from the farm to abattoir in modern livestock husbandry. The effects
of stress on the behavioral and physiological status and ultimate meat quality have been …

Redox reactions control fundamental processes of human biology. Therefore, it is safe to
assume that the responses and adaptations to exercise are, at least in part, mediated by …

Key points Nitric oxide (NO), a potent vasodilator and a regulator of many physiological
processes, is produced in mammals both enzymatically and by reduction of nitrite and nitrate …

Nitric oxide (NO) contributes to carbohydrate metabolism and decreased NO bioavailability
is involved in the development of type 2 diabetes mellitus (T2DM). NO donors may improve …

Previous studies have shown that nitric oxide (NO) supplements may prevent bone loss and
fractures in preclinical models of estrogen deficiency. However, the mechanisms by which …

Skeletal muscle plays a fundamental role in mobility, disease prevention, and quality of life.
Skeletal muscle mass is, in part, determined by the rates of protein synthesis, and …