Clinical significance of analysis of vitamin D status in various diseases

M Kowalówka, AK Główka, M Karaźniewicz-Łada… - Nutrients, 2020 - mdpi.com
Vitamin D plays a role not only in the proper functioning of the skeletal system and the
calcium-phosphate equilibrium, but also in the immune system, the cardiovascular system …

Effect of epigenetics on vitamin D levels: a systematic review until December 2020

A Forouhari, M Heidari-Beni, S Veisi, P Poursafa… - Archives of Public …, 2023 - Springer
Background The association between epigenetic modification of the genes involved in the
vitamin D metabolic pathway and vitamin D metabolites' status has been elucidated …

Effects of long-term vitamin D supplementation on metabolic profile in middle-aged and elderly patients with type 2 diabetes

Z Hu, X Zhi, J Li, B Li, J Wang, J Zhu, Z Zhang - The Journal of Steroid …, 2023 - Elsevier
To evaluate the effects of long-term vitamin D supplementation on metabolic profiles in
middle-aged to elderly patients with type 2 diabetes (T2D), a randomized controlled trial was …

Variability in response to vitamin D supplementation according to vitamin D metabolism related gene polymorphisms in healthy adults

M Ammar, S Heni, MS Tira, Y Khalij… - European Journal of …, 2023 - nature.com
Objective The aim of this study was to determine the influence of polymorphisms in some
key gene actors of the vitamin D (vitD) metabolic pathway on supplementation efficacy …

The Association between Polymorphisms of Vitamin D Metabolic‐Related Genes and Vitamin D3 Supplementation in Type 2 Diabetic Patients

Z Hu, SS Tao, H Liu, G Pan, B Li… - Journal of diabetes …, 2019 - Wiley Online Library
Objective. To investigate the effect of single nucleotide polymorphisms (SNPs) of the key
genes in vitamin D metabolic pathway on the serum 25 (OH) D level after long‐term vitamin …

Associations of vitamin D binding protein variants with the vitamin D-induced increase in serum 25-hydroxyvitamin D

M Mehramiz, SS Khayyatzadeh, H Esmaily… - Clinical nutrition …, 2019 - Elsevier
Background Vitamin D deficiency is a global problem that may be improved by vitamin D
supplementation; however, the individual's response to the intervention varies. We aimed to …

Association study between genetic variants in vitamin D metabolism related genes and childhood autism spectrum disorder

H Yu, Z Zhang, J Liu, P Hu, Z Liu - Metabolic brain disease, 2020 - Springer
Vitamin D deficiency has been implicated as a risk factor for autism spectrum disorder
(ASD). This case-controlled study was to determine the association between single …

Vitamin D3 supplementation had no benefits in patients with metabolic syndrome and vitamin D deficiency: A pilot study

SLS Aquino, ATO Cunha, KCM Sena-Evangelista… - Clinical Nutrition …, 2023 - Elsevier
Background Vitamin D deficiency has been observed in individuals with metabolic
syndrome (MetS). This study evaluated the effects of vitamin D supplementation in patients …

The impact of genetic variants related to vitamin D and autoimmunity: A systematic review

LM Trefilio, L Bottino, R de Carvalho Cardoso… - Heliyon, 2024 - cell.com
Over the past few years, there has been a notable increment in scientific literature aimed at
unraveling the genetic foundations of vitamin D signaling and its implications for …

Common polymorphisms in genes related to vitamin D metabolism affect the response of cognitive abilities to vitamin D supplementation

A Bahrami, SS Khayyatzadeh, N Jaberi… - Journal of Molecular …, 2019 - Springer
It is possible that vitamin D acts as a neurosteroid and that vitamin D deficiency may have an
adverse impact on brain function and cognitive function. There are a few reports that have …