Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa

S Hall, C McDermott, S Anoopkumar-Dukie… - Toxins, 2016 - mdpi.com
Pyocyanin has recently emerged as an important virulence factor produced by
Pseudomonas aeruginosa. The redox-active tricyclic zwitterion has been shown to have a …

Metabolites from symbiotic bacteria

J Piel - Natural product reports, 2009 - pubs.rsc.org
Metabolites from symbiotic bacteria - Natural Product Reports (RSC Publishing) DOI:10.1039/B703499G
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B703499G …

Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections

B Rada, TL Leto - Trends in microbiology, 2013 - cell.com
Pseudomonas aeruginosa (PA) uses several virulence factors to establish chronic
respiratory infections in bronchiectasis, chronic obstructive pulmonary disease, and cystic …

Airway surface liquid pH regulation in airway epithelium current understandings and gaps in knowledge

M Zajac, E Dreano, A Edwards, G Planelles… - International journal of …, 2021 - mdpi.com
Knowledge on the mechanisms of acid and base secretion in airways has progressed
recently. The aim of this review is to summarize the known mechanisms of airway surface …

Color me bad: microbial pigments as virulence factors

GY Liu, V Nizet - Trends in microbiology, 2009 - cell.com
A hallmark feature of several pathogenic microbes is the distinctive color of their colonies
when propagated in the clinical laboratory. Such pigmentation comes in a variety of hues …

Pseudomonas aeruginosa in Cystic Fibrosis Patients With G551D-CFTR Treated With Ivacaftor

SL Heltshe, N Mayer-Hamblett, JL Burns… - Clinical infectious …, 2015 - academic.oup.com
Background. Ivacaftor improves outcomes in cystic fibrosis (CF) patients with the G551D
mutation; however, effects on respiratory microbiology are largely unknown. This study …

Pseudomonas aeruginosa lipopolysaccharide: a major virulence factor, initiator of inflammation and target for effective immunity

GB Pier - International journal of medical microbiology, 2007 - Elsevier
Pseudomonas aeruginosa is one of the most important bacterial pathogens encountered by
immunocompromised hosts and patients with cystic fibrosis (CF), and the lipopolysaccharide …

Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients

TS Murray, M Egan, BI Kazmierczak - Current opinion in pediatrics, 2007 - journals.lww.com
Pseudomonas aeruginosa chronic colonization in cystic fibros... : Current Opinion in Pediatrics
Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients : Current Opinion in …

Pseudomonas aeruginosa Elastase Provides an Escape from Phagocytosis by Degrading the Pulmonary Surfactant Protein-A

Z Kuang, Y Hao, BE Walling, JL Jeffries, DE Ohman… - PloS one, 2011 - journals.plos.org
Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute pneumonitis
in immunocompromised patients and chronic lung infections in individuals with cystic …

The role of quorum sensing in chronic cystic fibrosis Pseudomonas aeruginosa infections

C Winstanley, JL Fothergill - FEMS microbiology letters, 2009 - academic.oup.com
Studies on cultured cells and in infection models have shown that cell density-dependent
quorum-sensing (QS) controls many of the known virulence factors of Pseudomonas …