Interleukin-12 (IL-12) is a potent, pro-inflammatory type 1 cytokine that has long been
studied as a potential immunotherapy for cancer. Unfortunately, IL-12's remarkable …

Incidents of viral outbreaks have increased at an alarming rate over the past decades. The
most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread …

Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

20 months has been passed since the detection of the first cases of SARS-CoV-2 infection
named COVID-19 from Wuhan city of China. This novel coronavirus spread rapidly around …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Breast cancer is considered one of the utmost neoplastic diseases globally, with a high
death rate of patients. Over the last decades, many approaches have been studied to early …

Since the first report on the pharmacological activity of curcumin in 1949, enormous amounts
of research have reported diverse activities for this natural polyphenol found in the dietary …

Topoisomerase enzymes have shown unique roles in replication and transcription. These
enzymes which were initially found in Escherichia coli have attracted considerable attention …

Leishmaniasis has infected more than 12 million people worldwide. This neglected tropical
disease, causing 20,000–30,000 deaths per year, is a global health problem. The …

Background Electrospinning has provided an excellent opportunity to develop nano-sized
fibers with a broad range of applications, including nano-drug delivery systems for the …