Redox-Linked Coordination Chemistry Directs Vitamin B12 Trafficking
Conspectus Metals are partners for an estimated one-third of the proteome and vary in
complexity from mononuclear centers to organometallic cofactors. Vitamin B12 or cobalamin …
complexity from mononuclear centers to organometallic cofactors. Vitamin B12 or cobalamin …
Mechanisms and Opportunities for Rational In Silico Design of Enzymes to Degrade Per-and Polyfluoroalkyl Substances (PFAS)
M Marciesky, DS Aga, IM Bradley… - Journal of Chemical …, 2023 - ACS Publications
Per and polyfluoroalkyl substances (PFAS) present a unique challenge to remediation
techniques because their strong carbon–fluorine bonds make them difficult to degrade. This …
techniques because their strong carbon–fluorine bonds make them difficult to degrade. This …
Differences in the formation of reactive oxygen species and their cytotoxicity between thiols combined with aqua-and cyanocobalamins
YV Shatalin, VS Shubina, ME Solovieva… - International Journal of …, 2022 - mdpi.com
Cobalamin is an essential nutrient required for the normal functioning of cells. Its deficiency
can lead to various pathological states. Hydroxocobalamin (HOCbl) and cyanocobalamin …
can lead to various pathological states. Hydroxocobalamin (HOCbl) and cyanocobalamin …
Versatile enzymology and heterogeneous phenotypes in cobalamin complementation type C disease
AJ Esser, S Mukherjee, IA Dereven'kov, SV Makarov… - Iscience, 2022 - cell.com
Nutritional deficiency and genetic errors that impair the transport, absorption, and utilization
of vitamin B 12 (B 12) lead to hematological and neurological manifestations. The cblC …
of vitamin B 12 (B 12) lead to hematological and neurological manifestations. The cblC …
A Noble Metal Substitution Leads to B12 Cofactor Mimicry by a Rhodibalamin
M Ruetz, R Mascarenhas, F Widner, C Kieninger… - Biochemistry, 2024 - ACS Publications
In mammals, cobalamin is an essential cofactor that is delivered by a multitude of
chaperones in an elaborate trafficking pathway to two client enzymes, methionine synthase …
chaperones in an elaborate trafficking pathway to two client enzymes, methionine synthase …
[HTML][HTML] The cobalamin processing enzyme of Trichoplax adhaerens
C Krams, AJ Esser, M Klenzendorf, K Klotz… - Journal of Biological …, 2024 - Elsevier
Cobalamin (Cbl) is an essential cofactor for methionine synthase (MS) and methylmalonyl-
CoA mutase (MUT), but it must first undergo chemical processing for utilization in animals. In …
CoA mutase (MUT), but it must first undergo chemical processing for utilization in animals. In …
A Comparative Study of ROS Production and Cytotoxicity Induced by Combinations of Thiols with HOCbl and CNCbl
YV Shatalin, VS Shubina, ME Solovieva, VS Akatov - 2022 - preprints.org
Cobalamin is an essential nutrient required for the normal functioning of cells. Its deficiency
can lead to various pathological states. Hydroxocobalamin (HOCbl) and cyanocobalamin …
can lead to various pathological states. Hydroxocobalamin (HOCbl) and cyanocobalamin …