Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions
SA Sakowski, EJ Koubek, KS Chen… - Annals of …, 2024 - Wiley Online Library
Neurodegenerative diseases are increasing in prevalence and place a significant burden on
society. The causes are multifactorial and complex, and increasing evidence suggests a …
society. The causes are multifactorial and complex, and increasing evidence suggests a …
[HTML][HTML] High-quality models for assessing the effects of environmental pollutants on the nervous system: 3D brain organoids
Y Yan, Z Yang, L Chen - Ecotoxicology and Environmental Safety, 2024 - Elsevier
The prevalence of environmental problems and the increasing risk of human exposure to
environmental pollutants have become a global concern. The increasing environmental …
environmental pollutants have become a global concern. The increasing environmental …
Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study
Introduction Environmental exposures strongly influence ALS risk and identification is
needed to reduce ALS burden. Participation in hobbies and exercise may alter ALS risk and …
needed to reduce ALS burden. Participation in hobbies and exercise may alter ALS risk and …
Case-control study of environmental toxins and risk of amyotrophic lateral sclerosis involving the national ALS registry
EO Talbott, AM Malek, VC Arena, F Wu… - … Lateral Sclerosis and …, 2024 - Taylor & Francis
Objective: Neurotoxic chemicals are suggested in the etiology of amyotrophic lateral
sclerosis (ALS). We examined the association of environmental and occupational risk factors …
sclerosis (ALS). We examined the association of environmental and occupational risk factors …
[HTML][HTML] Metal mixtures associate with higher amyotrophic lateral sclerosis risk and mortality independent of genetic risk and correlate to self-reported exposures: a …
Background: The pathogenesis of amyotrophic lateral sclerosis (ALS) involves both genetic
and environmental factors. This study investigates associations between metal measures in …
and environmental factors. This study investigates associations between metal measures in …
Mendelian randomization analysis suggests no associations of human herpes viruses with amyotrophic lateral sclerosis
Q Zheng, D Wang, R Lin, Y Chen, H Huang… - Frontiers in …, 2023 - frontiersin.org
Background The causal associations between infections with human herpes viruses (HHVs)
and amyotrophic lateral sclerosis (ALS) has been disputed. This study investigated the …
and amyotrophic lateral sclerosis (ALS) has been disputed. This study investigated the …
Update on recent advances in amyotrophic lateral sclerosis
In the last few years, our understanding of disease molecular mechanisms underpinning
ALS has advanced greatly, allowing the first steps in translating into clinical practice novel …
ALS has advanced greatly, allowing the first steps in translating into clinical practice novel …
Nanoplastics and Neurodegeneration in ALS
Plastic production, which exceeds one million tons per year, is of global concern. The
constituent low-density polymers enable spread over large distances and micro/nano …
constituent low-density polymers enable spread over large distances and micro/nano …
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Background: Environmental exposures impact amyotrophic lateral sclerosis (ALS) risk and
progression, a fatal and progressive neurodegenerative disease. Better characterization of …
progression, a fatal and progressive neurodegenerative disease. Better characterization of …
Occupational lead exposure and amyotrophic lateral sclerosis survival in the Danish National Patient Registry
IW Tang, J Hansen, AS Dickerson… - … Lateral Sclerosis and …, 2024 - Taylor & Francis
Objectives We investigated the relationship between occupational lead exposure and
amyotrophic lateral sclerosis (ALS) survival in Denmark. Methods We identified 2,161 ALS …
amyotrophic lateral sclerosis (ALS) survival in Denmark. Methods We identified 2,161 ALS …