Natural killer (NK) cells are innate lymphocytes that play a critical role in early host defense
against viruses. Through their cytolytic capacity and generation of cytokines and …

The immune system has crucial roles in the pathogenesis of multiple sclerosis. While the
adaptive immune cell subsets, T and B cells, have been the main focus of immunological …

Recent evidence indicates that natural killer (NK) cells can negatively regulate T-cell
responses, but the mechanisms behind this phenomenon as a consequence of NK–T-cell …

In mouse models of chronic inflammatory diseases, Natural Killer (NK) cells can play an
immunoregulatory role by eliminating chronically activated leukocytes. Indirect evidence …

In autoimmunity, the balance of different helper T (Th) cell subsets can influence the tissue
damage caused by autoreactive T cells. Pro-inflammatory Th1 and Th17 T cells are …

Natural killer (NK) cells are critical players during tumor growth control in immunocompetent
hosts. These cells also establish a cross-talk with dendritic cells (DCs) and promote a Th1 …

An ever growing number of reports on graft rejection and/or failure even with good HLA
matches have highlighted an important role of non-HLA antigens in influencing allograft …

We previously demonstrated a correlation between the frequency of CX3CR1‐expressing
human natural killer (NK) cells and disease activity in multiple sclerosis and showed that …

CD3-negative NK cells are granular lymphocytes capable of producing inflammatory
cytokines and killing malignant, infected, or stressed cells. We have recently observed a new …

Even when kidney allografts are well matched for human leukocyte antigen (HLA) and anti-
HLA antibodies are not detected, graft rejection can still occur. There is evidence that some …