First performed in 1963, lung transplantation is approaching the half-century mark. With
more than 32,000 procedures having been performed worldwide, lung transplantation has …

Infectious diseases after solid organ transplantation (SOT) are a significant cause of
morbidity and reduced allograft and patient survival; however, the influence of infection on …

Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that
is associated with poor survival. The International Society for Heart and Lung …

Although survival after lung transplantation has improved significantly during the last
decade, chronic rejection is thought to be the major cause of late mortality. The physiologic …

Rationale: Long-term survival after lung transplantation is limited by infectious complications
and by bronchiolitis obliterans syndrome (BOS), a form of chronic rejection linked in part to …

Few studies have examined the lung virome in health and disease. Outcomes of lung
transplantation are known to be influenced by several recognized respiratory viruses, but …

The field of cardiothoracic transplantation (CT) has evolved significantly, but infections
remain an important cause of morbidity and mortality, particularly fungal infections (FIs). The …

Aspergillus colonization of the lower respiratory airways is common in normal people, and of
little clinical significance. However, in some patients, colonization is associated with severe …

Bronchiolitis obliterans syndrome (BOS) is a form of chronic lung allograft dysfunction that
affects a majority of lung transplant recipients and is the principal factor limiting long-term …