Clinical history, questionnaire data and response to antisecretory therapy are insufficient to
make a conclusive diagnosis of GERD in isolation, but are of value in determining need for …

Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate
into the esophagus or beyond, resulting in either troublesome symptoms or complications …

Management of gastroesophageal reflux disease (GERD) commonly starts with an empiric
trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for …

Up to 40% of patients with symptoms suspicious of gastroesophageal reflux disease (GERD)
do not respond completely to proton pump inhibitor (PPI) therapy. The term “refractory …

Background Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a
frequent clinical problem with multiple potential causes. Treatments for PPI-refractory …

GERD is a common condition worldwide. Key mechanisms of disease include abnormal
oesophagogastric junction structure and function, and impaired oesophageal clearance. A …

Эволюция представлений о функциональных заболеваниях желудочно-кише Page 1 Лекции
и обзоры / Lectures and reviews 4 www.gastro-j.ru Рос журн гастроэнтерол гепатол …

Objective Antireflux surgery can be proposed in patients with GORD, especially when proton
pump inhibitor (PPI) use leads to incomplete symptom improvement. However, to date …

Reflux hypersensitivity, recently introduced by Rome IV as a new functional esophageal
disorder, is currently considered as the presence of typical heartburn symptoms in patients …

Keywords: FUNCTIONAL DISEASES OF THE DIGESTIVE SYSTEM, FUNCTIONAL
HEARTBURN, FUNCTIONAL DYSPEPSIA, BILIARY DYSFUNCTION, IRRITABLE BOWEL …