Recent advances in 4 (3 H)-quinazolinone syntheses

L He, H Li, J Chen, XF Wu - RSC advances, 2014 - pubs.rsc.org
The 4 (3H)-quinazolinone is a frequently encountered heterocycle with broad applications
including antimalarial, antitumor, anticonvulsant, fungicidal, antimicrobial, and anti …

Recent developments regarding the use of thieno [2, 3-d] pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties

K Bozorov, JY Zhao, B Elmuradov, A Pataer… - European Journal of …, 2015 - Elsevier
It is generally understood that the antitumor properties of synthetic heterocyclic compounds
are among the most powerful properties that can be made use in medicinal chemistry. More …

Facile synthesis of 1, 4-benzodiazepine-2, 5-diones and quinazolinones from amino acids as anti-tubercular agents

SM Anil, R Shobith, KR Kiran, TR Swaroop… - New Journal of …, 2019 - pubs.rsc.org
A family of 1, 4-benzodiazepine-2, 5-diones and quinazolinones with diverse substituents at
the C-3 position were synthesized via a novel, simple and convenient methodology using …

Ionic liquid promoted eco-friendly and efficient synthesis of six-membered N-polyheterocycles

N Kaur - Current Organic Synthesis, 2018 - ingentaconnect.com
Background: The synthesis of N-polyheterocycles by environmentally benign method is
highly attractive but challenging proposition. New strategies have been developed for the …

[HTML][HTML] Synthesis, in-silico, and in-vitro study of novel chloro methylquinazolinones as PI3K-δ inhibitors, cytotoxic agents

SM Elfeky, SJ Almehmadi, SS Tawfik - Arabian Journal of Chemistry, 2022 - Elsevier
Through a two-step procedure, 3-amino-7-chloro-2-methylquinazolin-4 (3H)-one was
synthesized from 2-amino-4-chlorobenzoic acid as a starting material. The latter reacted with …

Recent Advances on Diversity Oriented Heterocycle Synthesis of Fused Quinazolinones

MH Alhalafi - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
During the last decade quinazolinones derivatives have been shown to be useful building
blocks for the synthesis of a variety of functionalized polynuclear heterocyclic systems. This …

One-pot Synthesis of 2, 3-disubstituted-4 (3H)-quinazolinone from o-aminobenzoic Acid and DMF Derivatives using Imidazole Hydrochloride as a Promoter

Y Wang, X Zhang, S Li, M Guo, W Ma… - Current Organic …, 2024 - ingentaconnect.com
As a novel and environmentally friendly Brönsted acid, imidazole hydrochloride was used to
promote the synthesis of 2, 3-disubstituted-4 (3H)-quinazolinone from o-aminobenzoic acid …

Improved Rapid and Green Synthesis of N‐Aryl Piperazine Hydrochlorides Using Synergistic Coupling of Hydrated Task Specific Ionic Liquid ([BbIm]OH) and …

RS Tamboli, MM Shidore, RC Dash… - …, 2019 - Wiley Online Library
An improved and rapid green synthesis of N‐alkyl/aryl piperazine hydrochlorides using
synergistic coupling of hydrated Task Specific Ionic Liquid ([BbIm] OH) and Microwave …

[PDF][PDF] Sulfonate derived phosphoramidates as active intermediates in the enzymatic primer-extension of DNA

S De, E Groaz, L Margamuljana… - Organic & …, 2015 - lirias.kuleuven.be
Novel unnatural 5'-phosphoramidate nucleosides, capable of being processed as substrates
by DNA polymerases for multiple nucleotide incorporations, have been designed. The …