The cornea is the outmost layer of the eye, unique in its transparency and strength. The
cornea not only transmits the light essential for vision, also refracts light, giving focus to …

Corneal failure is a highly prevalent cause of blindness. One special cause of corneal failure
occurs due to malfunction or destruction of the limbal stem cell niche, upon which the …

The cornea is the outermost layer of the eye and plays an essential role in our visual system.
Limbal epithelial stem cells (LESCs), which are localized to a highly regulated limbal niche …

Maintenance of the visual function is the desired outcome of ophthalmologic therapies. The
shortcomings of the current treatment options, like partial recovery, post-operation failure …

A hybrid scaffold of gelatin-glycosaminoglycan matrix and fibrin (FGG) has been synthesized
to improve the mechanical properties, degradation time and cell response of fibrin-like …

Methods: PubMed was searched for publications using the terms LSCD, cell-based therapy,
cultivated limbal epithelial transplantation (CLET), cultivated oral mucosal epithelial …

Corneal stem/progenitor cells are typical adult stem/progenitor cells. The human cornea
covers the front of the eyeball, which protects the eye from the outside environment while …

Purpose To review the surgical management options in ocular chemical burn, including
newer advances. Methods Online literature search of published articles over last 5 years on …

Introduction: Corneal limbal stem cell deficiency is a multifaceted, sight-threatening disease
process that can be challenging to diagnose and treat. Areas covered: This review …

Background and Objective: Limbal stem cell deficiency (LSCD) is characterized by the
insufficiency of limbal stem cells to maintain the corneal epithelium. Severe cases of LSCD …