Natural product synthesis has lain at the heart of organic chemistry. Complex structures of
natural products have inspired chemists to develop new methods and strategies. The utility …

Fused tricyclic indole frameworks are found in various bioactive natural products and
pharmaceuticals. The development of an efficient synthetic method for this structural motif …

3, 4-Fused tricyclic indole scaffolds are ubiquitous in bioactive natural products and
pharmaceuticals. A new protocol for the synthesis of 3, 4-fused tricyclic indoles has been …

A simple one-pot, two-step strategy for the synthesis of tetrahydro-1 H-azepino [4, 3, 2-cd]
indoles via Lewis acid-catalyzed SN2-type ring opening of activated azetidines with 4 …

Aryl hydrazides with a ketone or aldehyde containing side chains linked to the meta-position
of the aromatic ring undergo acid-promoted intramolecular Fischer indole synthesis to …

The controllable intramolecular amidoarylation and hydroarylation of alkynes has been
achieved via rhodium (III)-catalyzed C–H activation. The merger of two distinct reaction …

The rhodium (III)-catalyzed intramolecular annulation of alkyne-tethered acetanilides for the
synthesis of fused tricyclic indole scaffolds via C–H activation has been developed, which …

Many naturally occurring indole alkaloids and biologically interesting compounds, such as
the ergot alkaloids, contain the C 3/C 4-annulated indole scaffold. These important …

Pyrroloazocine indole alkaloids consisting of eight-membered azacycle fused to pyrrole and
indole units exhibit intriguing pharmacological functions but still pose a synthetic challenge …

A novel Pd-catalyzed cascade cyclization by intramolecular Heck insertion of an allene–
allylic amination sequence was developed. Allenes tethered to ortho-iodoaniline derivatives …