Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …

Omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are
found naturally in fish oil and are commonly thought to be anti-inflammatory nutrients, with …

Acute inflammation in the lung is essential to health. So too is its resolution. In response to
invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is …

The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …

Complete resolution of an acute inflammatory response and its return to homeostasis are
essential for healthy tissues. Here, we overview ongoing efforts to characterize cellular and …

Inflammation and its timely resolution are critical to ensure effective host defense and
appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation …

Resolution of inflammation has historically been viewed as a passive process, occurring as
a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as …

Improved understanding of the role of inflammation in tendon disease is required to facilitate
therapeutic target discovery. We studied supraspinatus tendons from patients experiencing …

The resolution of inflammation is an active process controlled by endogenous mediators
with selective actions on neutrophils and monocytes. The initial phase of the acute …

We discuss the fascinating pharmacology of formylpeptide receptor 2 (FPR2; often referred
to as FPR2/ALX since it binds lipoxin A4). Initially identified as a low‐affinity 'relative'of …