[HTML][HTML] Specialized pro-resolving mediators: endogenous regulators of infection and inflammation
MC Basil, BD Levy - Nature Reviews Immunology, 2016 - nature.com
Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …
[HTML][HTML] Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases
Omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are
found naturally in fish oil and are commonly thought to be anti-inflammatory nutrients, with …
found naturally in fish oil and are commonly thought to be anti-inflammatory nutrients, with …
Resolution of acute inflammation in the lung
BD Levy, CN Serhan - Annual review of physiology, 2014 - annualreviews.org
Acute inflammation in the lung is essential to health. So too is its resolution. In response to
invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is …
invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is …
Lipoxins and aspirin-triggered lipoxins in resolution of inflammation
M Romano, E Cianci, F Simiele, A Recchiuti - European journal of …, 2015 - Elsevier
The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …
Endogenous pro‐resolving and anti‐inflammatory lipid mediators: a new pharmacologic genus
Complete resolution of an acute inflammatory response and its return to homeostasis are
essential for healthy tissues. Here, we overview ongoing efforts to characterize cellular and …
essential for healthy tissues. Here, we overview ongoing efforts to characterize cellular and …
Lipoxin mimetics and the resolution of inflammation
Inflammation and its timely resolution are critical to ensure effective host defense and
appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation …
appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation …
Resolvins and protectins: mediating solutions to inflammation
P Kohli, BD Levy - British journal of pharmacology, 2009 - Wiley Online Library
Resolution of inflammation has historically been viewed as a passive process, occurring as
a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as …
a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as …
Inflammation activation and resolution in human tendon disease
Improved understanding of the role of inflammation in tendon disease is required to facilitate
therapeutic target discovery. We studied supraspinatus tendons from patients experiencing …
therapeutic target discovery. We studied supraspinatus tendons from patients experiencing …
Lipoxins: resolutionary road
P Maderna, C Godson - British journal of pharmacology, 2009 - Wiley Online Library
The resolution of inflammation is an active process controlled by endogenous mediators
with selective actions on neutrophils and monocytes. The initial phase of the acute …
with selective actions on neutrophils and monocytes. The initial phase of the acute …
Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35
CX Qin, LV Norling, EA Vecchio… - British Journal of …, 2022 - Wiley Online Library
We discuss the fascinating pharmacology of formylpeptide receptor 2 (FPR2; often referred
to as FPR2/ALX since it binds lipoxin A4). Initially identified as a low‐affinity 'relative'of …
to as FPR2/ALX since it binds lipoxin A4). Initially identified as a low‐affinity 'relative'of …