Alzheimer's disease (AD) is a clinically heterogeneous neurodegenerative disease with a
strong genetic component. Several genes have been associated with AD risk for nearly 20 …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Aging is a prominent risk factor for neurodegenerative disorders (NDDs); however, the
molecular mechanisms rendering the aged brain particularly susceptible to …

Abstract The Genetics Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI),
formally established in 2009, aims to provide resources and facilitate research related to …

Preclinical changes that precede the onset of symptoms and eventual diagnosis of
Alzheimer's disease (AD) are a target for potential preventive interventions. A large body of …

Cerebrospinal fluid (CSF) 42 amino acid species of amyloid beta (Aβ42) and tau levels are
strongly correlated with the presence of Alzheimer's disease (AD) neuropathology including …

Alzheimer's disease is the most common form of dementia and is the only top 10 cause of
death in the United States that lacks disease‐altering treatments. It is a complex disorder …

Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most
common form of dementia in old age. The complexity and behavior of circular RNA …

Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in
longitudinal cohort epidemiological studies, and endocrinologic evidence suggests …

There is an extensive literature relating to factors associated with the development of
Alzheimer's disease (AD), but less is known about factors which may contribute to its …